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Splicing- and demethylase-independent functions of LSD1 in zebrafish primitive hematopoiesis
LSD1/KDM1A is a widely conserved lysine-specific demethylase that removes methyl groups from methylated proteins, mainly histone H3. We previously isolated the zebrafish LSD1 gene and demonstrated that it is required for primitive hematopoiesis. Recently, a neuron-specific splicing variant of LSD1 w...
Autores principales: | Tamaoki, Junya, Takeuchi, Miki, Abe, Ryo, Kaneko, Hiroshi, Wada, Taeko, Hino, Shinjiro, Nakao, Mitsuyoshi, Furukawa, Yusuke, Kobayashi, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244555/ https://www.ncbi.nlm.nih.gov/pubmed/32444613 http://dx.doi.org/10.1038/s41598-020-65428-9 |
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