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Of Mice and Monkeys: Neuroprotective Efficacy of the p38 Inhibitor BIRB 796 Depends on Model Duration in Experimental Glaucoma

Glaucoma is a group of optic neuropathies associated with aging and sensitivity to intraocular pressure (IOP). Early progression involves retinal ganglion cell (RGC) axon dysfunction that precedes frank degeneration. Previously we demonstrated that p38 MAPK inhibition abates axonal dysfunction and s...

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Detalles Bibliográficos
Autores principales: Lambert, Wendi S., Pasini, Silvia, Collyer, John W., Formichella, Cathryn R., Ghose, Purnima, Carlson, Brian J., Calkins, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244559/
https://www.ncbi.nlm.nih.gov/pubmed/32444682
http://dx.doi.org/10.1038/s41598-020-65374-6