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Dietary serine-microbiota interaction enhances chemotherapeutic toxicity without altering drug conversion

The gut microbiota metabolizes drugs and alters their efficacy and toxicity. Diet alters drugs, the metabolism of the microbiota, and the host. However, whether diet-triggered metabolic changes in the microbiota can alter drug responses in the host has been largely unexplored. Here we show that diet...

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Detalles Bibliográficos
Autores principales: Ke, Wenfan, Saba, James A., Yao, Cong-Hui, Hilzendeger, Michael A., Drangowska-Way, Anna, Joshi, Chintan, Mony, Vinod K., Benjamin, Shawna B., Zhang, Sisi, Locasale, Jason, Patti, Gary J., Lewis, Nathan, O’Rourke, Eyleen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244588/
https://www.ncbi.nlm.nih.gov/pubmed/32444616
http://dx.doi.org/10.1038/s41467-020-16220-w

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