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Dietary serine-microbiota interaction enhances chemotherapeutic toxicity without altering drug conversion
The gut microbiota metabolizes drugs and alters their efficacy and toxicity. Diet alters drugs, the metabolism of the microbiota, and the host. However, whether diet-triggered metabolic changes in the microbiota can alter drug responses in the host has been largely unexplored. Here we show that diet...
Autores principales: | Ke, Wenfan, Saba, James A., Yao, Cong-Hui, Hilzendeger, Michael A., Drangowska-Way, Anna, Joshi, Chintan, Mony, Vinod K., Benjamin, Shawna B., Zhang, Sisi, Locasale, Jason, Patti, Gary J., Lewis, Nathan, O’Rourke, Eyleen J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244588/ https://www.ncbi.nlm.nih.gov/pubmed/32444616 http://dx.doi.org/10.1038/s41467-020-16220-w |
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