HnRNP F/H associate with hTERC and telomerase holoenzyme to modulate telomerase function and promote cell proliferation

Human telomerase RNA component hTERC comprises multiple motifs that contribute to hTERC biogenesis, holoenzyme activity, and enzyme recruitment to telomeres. hTERC contains several guanine tracts (G-tracts) at its 5′-end, but its associated proteins and potential roles in telomerase function are sti...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Chenzhong, Xie, Nan, Su, Yuanyuan, Sun, Zhaomeng, Liang, Yao, Zhang, Na, Liu, Doudou, Jia, Shuqin, Xing, Xiaofang, Han, Limin, Li, Guodong, Tong, Tanjun, Chen, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244589/
https://www.ncbi.nlm.nih.gov/pubmed/31863069
http://dx.doi.org/10.1038/s41418-019-0483-6

Ejemplares similares

Ejemplares similares