Mitochondrial stress-activated cGAS-STING pathway inhibits thermogenic program and contributes to overnutrition-induced obesity in mice

Obesity is a global epidemic that is caused by excessive energy intake or inefficient energy expenditure. Brown or beige fat dissipates energy as heat through non-shivering thermogenesis by their high density of mitochondria. However, how the mitochondrial stress-induced signal is coupled to the cel...

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Detalles Bibliográficos
Autores principales: Bai, Juli, Cervantes, Christopher, He, Sijia, He, Jieyu, Plasko, George R., Wen, Jie, Li, Zhi, Yin, Dongqing, Zhang, Chuntao, Liu, Meilian, Dong, Lily Q., Liu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244732/
https://www.ncbi.nlm.nih.gov/pubmed/32444826
http://dx.doi.org/10.1038/s42003-020-0986-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244732/
https://www.ncbi.nlm.nih.gov/pubmed/32444826
http://dx.doi.org/10.1038/s42003-020-0986-1

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