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KAT3-dependent acetylation of cell type-specific genes maintains neuronal identity in the adult mouse brain
The lysine acetyltransferases type 3 (KAT3) family members CBP and p300 are important transcriptional co-activators, but their specific functions in adult post-mitotic neurons remain unclear. Here, we show that the combined elimination of both proteins in forebrain excitatory neurons of adult mice r...
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244750/ https://www.ncbi.nlm.nih.gov/pubmed/32444594 http://dx.doi.org/10.1038/s41467-020-16246-0 |