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Differential DNA methylation correlates with response to methotrexate in rheumatoid arthritis

OBJECTIVES: Identifying blood-based biomarkers that predict treatment response in RA is a clinical priority. We investigated differential DNA methylation as a candidate biomarker of response for the first-line drug used in RA, MTX. METHODS: DNA methylation was measured in DNA samples from individual...

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Detalles Bibliográficos
Autores principales:	Nair, Nisha, Plant, Darren, Verstappen, Suzanne M, Isaacs, John D, Morgan, Ann W, Hyrich, Kimme L, Barton, Anne, Wilson, Anthony G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Clinical Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244777/ https://www.ncbi.nlm.nih.gov/pubmed/31598719 http://dx.doi.org/10.1093/rheumatology/kez411

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