COVID-19: Loss of bridging between innate and adaptive immunity?

COVID-19 has spread to most countries in the world. However, there are some striking differences in how COVID-19 is behaving in different age groups. While data on COVID-19 is limited, children appear to be less susceptible to severe disease. These unique characteristics may be considered as a poten...

Descripción completa

Detalles Bibliográficos
Autores principales: Rao, Vishal U.S, Arakeri, Gururaj, Subash, Anand, Rao, Jyothsna, Jadhav, Sachin, Suhail Sayeed, Mufti, Rao, Gururaj, Brennan, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245229/
https://www.ncbi.nlm.nih.gov/pubmed/32505066
http://dx.doi.org/10.1016/j.mehy.2020.109861
_version_ 1783537712924459008
author Rao, Vishal U.S
Arakeri, Gururaj
Subash, Anand
Rao, Jyothsna
Jadhav, Sachin
Suhail Sayeed, Mufti
Rao, Gururaj
Brennan, Peter A.
author_facet Rao, Vishal U.S
Arakeri, Gururaj
Subash, Anand
Rao, Jyothsna
Jadhav, Sachin
Suhail Sayeed, Mufti
Rao, Gururaj
Brennan, Peter A.
author_sort Rao, Vishal U.S
collection PubMed
description COVID-19 has spread to most countries in the world. However, there are some striking differences in how COVID-19 is behaving in different age groups. While data on COVID-19 is limited, children appear to be less susceptible to severe disease. These unique characteristics may be considered as a potential link to understanding the immune system and response in COVID-19 and lead to an effective cure to the disease. We suggest a possible role of loss of bridging between innate and adaptive immunity in COVID-19 and a potential treatment modality also discussed.
format Online
Article
Text
id pubmed-7245229
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Elsevier Ltd.
record_format MEDLINE/PubMed
spelling pubmed-72452292020-05-26 COVID-19: Loss of bridging between innate and adaptive immunity? Rao, Vishal U.S Arakeri, Gururaj Subash, Anand Rao, Jyothsna Jadhav, Sachin Suhail Sayeed, Mufti Rao, Gururaj Brennan, Peter A. Med Hypotheses Article COVID-19 has spread to most countries in the world. However, there are some striking differences in how COVID-19 is behaving in different age groups. While data on COVID-19 is limited, children appear to be less susceptible to severe disease. These unique characteristics may be considered as a potential link to understanding the immune system and response in COVID-19 and lead to an effective cure to the disease. We suggest a possible role of loss of bridging between innate and adaptive immunity in COVID-19 and a potential treatment modality also discussed. Elsevier Ltd. 2020-11 2020-05-23 /pmc/articles/PMC7245229/ /pubmed/32505066 http://dx.doi.org/10.1016/j.mehy.2020.109861 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Rao, Vishal U.S
Arakeri, Gururaj
Subash, Anand
Rao, Jyothsna
Jadhav, Sachin
Suhail Sayeed, Mufti
Rao, Gururaj
Brennan, Peter A.
COVID-19: Loss of bridging between innate and adaptive immunity?
title COVID-19: Loss of bridging between innate and adaptive immunity?
title_full COVID-19: Loss of bridging between innate and adaptive immunity?
title_fullStr COVID-19: Loss of bridging between innate and adaptive immunity?
title_full_unstemmed COVID-19: Loss of bridging between innate and adaptive immunity?
title_short COVID-19: Loss of bridging between innate and adaptive immunity?
title_sort covid-19: loss of bridging between innate and adaptive immunity?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245229/
https://www.ncbi.nlm.nih.gov/pubmed/32505066
http://dx.doi.org/10.1016/j.mehy.2020.109861
work_keys_str_mv AT raovishalus covid19lossofbridgingbetweeninnateandadaptiveimmunity
AT arakerigururaj covid19lossofbridgingbetweeninnateandadaptiveimmunity
AT subashanand covid19lossofbridgingbetweeninnateandadaptiveimmunity
AT raojyothsna covid19lossofbridgingbetweeninnateandadaptiveimmunity
AT jadhavsachin covid19lossofbridgingbetweeninnateandadaptiveimmunity
AT suhailsayeedmufti covid19lossofbridgingbetweeninnateandadaptiveimmunity
AT raogururaj covid19lossofbridgingbetweeninnateandadaptiveimmunity
AT brennanpetera covid19lossofbridgingbetweeninnateandadaptiveimmunity

Ejemplares similares