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Developing a multivariable prediction model for functional outcome after reperfusion therapy for acute ischaemic stroke: study protocol for the Targeting Optimal Thrombolysis Outcomes (TOTO) multicentre cohort study
INTRODUCTION: Intravenous thrombolysis (IVT) with recombinant tissue plasminogen activator (rt-PA) is the only approved pharmacological reperfusion therapy for acute ischaemic stroke. Despite population benefit, IVT is not equally effective in all patients, nor is it without significant risk. Uncert...
Autores principales: | Holliday, Elizabeth, Lillicrap, Thomas, Kleinig, Timothy, Choi, Philip M C, Maguire, Jane, Bivard, Andrew, Lincz, Lisa F, Hamilton-Bruce, Monica Anne, Rao, Sushma R, Snel, Marten F, Trim, Paul J, Lin, Longting, Parsons, Mark W, Worrall, Bradford B, Koblar, Simon, Attia, John, Levi, Chris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245375/ https://www.ncbi.nlm.nih.gov/pubmed/32265253 http://dx.doi.org/10.1136/bmjopen-2020-038180 |
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