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Molecular Insight into the Therapeutic Promise of Targeting APOE4 for Alzheimer's Disease
Alzheimer's disease (AD) is a progressive neurodegenerative disease that causes chronic cognitive dysfunction. Most of the AD cases are late onset, and the apolipoprotein E (APOE) isoform is a key genetic risk factor. The APOE gene has 3 key alleles in humans including APOE2, APOE3, and APOE4....
Autores principales: | Mamun, Abdullah Al, Uddin, Md. Sahab, Bin Bashar, Md. Fahim, Zaman, Sonia, Begum, Yesmin, Bulbul, Israt Jahan, Islam, Md. Siddiqul, Sarwar, Md. Shahid, Mathew, Bijo, Amran, Md. Shah, Md Ashraf, Ghulam, Bin-Jumah, May N., Mousa, Shaker A., Abdel-Daim, Mohamed M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245681/ https://www.ncbi.nlm.nih.gov/pubmed/32509144 http://dx.doi.org/10.1155/2020/5086250 |
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