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Molecular Insight into the Therapeutic Promise of Targeting APOE4 for Alzheimer's Disease

Alzheimer's disease (AD) is a progressive neurodegenerative disease that causes chronic cognitive dysfunction. Most of the AD cases are late onset, and the apolipoprotein E (APOE) isoform is a key genetic risk factor. The APOE gene has 3 key alleles in humans including APOE2, APOE3, and APOE4....

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Detalles Bibliográficos
Autores principales: Mamun, Abdullah Al, Uddin, Md. Sahab, Bin Bashar, Md. Fahim, Zaman, Sonia, Begum, Yesmin, Bulbul, Israt Jahan, Islam, Md. Siddiqul, Sarwar, Md. Shahid, Mathew, Bijo, Amran, Md. Shah, Md Ashraf, Ghulam, Bin-Jumah, May N., Mousa, Shaker A., Abdel-Daim, Mohamed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245681/
https://www.ncbi.nlm.nih.gov/pubmed/32509144
http://dx.doi.org/10.1155/2020/5086250

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