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Elucidation of the Molecular Mechanisms Underlying Sorafenib-Induced Hepatotoxicity
Sorafenib is a small, orally-active multikinase inhibitor that is most frequently used for the management of renal cell carcinoma, hepatocellular carcinoma, and radioactive iodine-resistant thyroid carcinoma. However, recent reports have associated sorafenib with hepatotoxicity that can limit its cl...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245685/ https://www.ncbi.nlm.nih.gov/pubmed/32509153 http://dx.doi.org/10.1155/2020/7453406 |