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Symphony of epigenetic and metabolic regulation—interaction between the histone methyltransferase EZH2 and metabolism of tumor

Increasing evidence has suggested that epigenetic and metabolic alterations in cancer cells are highly intertwined. As the master epigenetic regulator, enhancer of zeste homolog 2 (EZH2) suppresses gene transcription mainly by catalyzing the trimethylation of histone H3 at lysine 27 (H3K27me3) and e...

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Detalles Bibliográficos
Autores principales:	Zhang, Tengrui, Gong, Yueqing, Meng, Hui, Li, Chen, Xue, Lixiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245796/ https://www.ncbi.nlm.nih.gov/pubmed/32448308 http://dx.doi.org/10.1186/s13148-020-00862-0

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