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Cartilage-binding antibodies initiate joint inflammation and promote chronic erosive arthritis
BACKGROUND: Antibodies binding to cartilage proteins are present in the blood and synovial fluid of early rheumatoid arthritis patients. In order to develop animal models mimicking the human disease, we have characterized the arthritogenic capacity of monoclonal antibodies directed towards different...
Autores principales: | Li, Yanpeng, Tong, Dongmei, Liang, Peibin, Lönnblom, Erik, Viljanen, Johan, Xu, Bingze, Nandakumar, Kutty Selva, Holmdahl, Rikard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245816/ https://www.ncbi.nlm.nih.gov/pubmed/32448385 http://dx.doi.org/10.1186/s13075-020-02169-0 |
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