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Use of partitioned GMM marginal regression model with time-dependent covariates: analysis of Chinese Longitudinal Healthy Longevity Study

BACKGROUND: Elderly population’s health is a major concern for most industrial nations. National health surveys provide a measure of the state of elderly health. One such survey is the Chinese Longitudinal Healthy Longevity Survey. It collects data on risk factors and outcomes on the elderly. We exa...

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Autores principales: Vazquez-Arreola, Elsa, Xue, Dan, Wilson, Jeffrey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245823/
https://www.ncbi.nlm.nih.gov/pubmed/32448318
http://dx.doi.org/10.1186/s12874-020-01003-0
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author Vazquez-Arreola, Elsa
Xue, Dan
Wilson, Jeffrey R.
author_facet Vazquez-Arreola, Elsa
Xue, Dan
Wilson, Jeffrey R.
author_sort Vazquez-Arreola, Elsa
collection PubMed
description BACKGROUND: Elderly population’s health is a major concern for most industrial nations. National health surveys provide a measure of the state of elderly health. One such survey is the Chinese Longitudinal Healthy Longevity Survey. It collects data on risk factors and outcomes on the elderly. We examine these longitudinal survey data to determine the changes in health and to identify risk factors as they impact health outcomes including the elderly’s ability to do a physical check. METHODS: We use a Partitioned GMM logistic regression model to identify risk factors. The model also accounts for the correlation between lagged time-dependent covariates and the outcomes. It addresses present and past measures of time-dependent covariates on simultaneous outcomes. The relation produces additional regression coefficients as byproduct of the Partitioned model, identifying the immediate, delayed effects (lag − 1), further delayed (lag-2), etc. Therefore, the model presents the opportunity for decision makers to monitor the covariate over time. This technique is particularly useful in healthcare and health related research. We use the Chinese Longitudinal Health Longevity Survey data to identify those risk factors and to display the utility of the model. RESULTS: We found that one’s ability to make own decisions, frequently consuming vegetables, exercise frequently, one’s ability to transfer without assistance, having visual difficulties and being able to pick book from floor while standing had varying effects of significance on one’s health and ability to complete physical checks as they get older. CONCLUSIONS: The partitioning of the covariates as immediate effect, delayed effect or further delayed effect are important measures in a declining population.
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spelling pubmed-72458232020-06-01 Use of partitioned GMM marginal regression model with time-dependent covariates: analysis of Chinese Longitudinal Healthy Longevity Study Vazquez-Arreola, Elsa Xue, Dan Wilson, Jeffrey R. BMC Med Res Methodol Research Article BACKGROUND: Elderly population’s health is a major concern for most industrial nations. National health surveys provide a measure of the state of elderly health. One such survey is the Chinese Longitudinal Healthy Longevity Survey. It collects data on risk factors and outcomes on the elderly. We examine these longitudinal survey data to determine the changes in health and to identify risk factors as they impact health outcomes including the elderly’s ability to do a physical check. METHODS: We use a Partitioned GMM logistic regression model to identify risk factors. The model also accounts for the correlation between lagged time-dependent covariates and the outcomes. It addresses present and past measures of time-dependent covariates on simultaneous outcomes. The relation produces additional regression coefficients as byproduct of the Partitioned model, identifying the immediate, delayed effects (lag − 1), further delayed (lag-2), etc. Therefore, the model presents the opportunity for decision makers to monitor the covariate over time. This technique is particularly useful in healthcare and health related research. We use the Chinese Longitudinal Health Longevity Survey data to identify those risk factors and to display the utility of the model. RESULTS: We found that one’s ability to make own decisions, frequently consuming vegetables, exercise frequently, one’s ability to transfer without assistance, having visual difficulties and being able to pick book from floor while standing had varying effects of significance on one’s health and ability to complete physical checks as they get older. CONCLUSIONS: The partitioning of the covariates as immediate effect, delayed effect or further delayed effect are important measures in a declining population. BioMed Central 2020-05-24 /pmc/articles/PMC7245823/ /pubmed/32448318 http://dx.doi.org/10.1186/s12874-020-01003-0 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Vazquez-Arreola, Elsa
Xue, Dan
Wilson, Jeffrey R.
Use of partitioned GMM marginal regression model with time-dependent covariates: analysis of Chinese Longitudinal Healthy Longevity Study
title Use of partitioned GMM marginal regression model with time-dependent covariates: analysis of Chinese Longitudinal Healthy Longevity Study
title_full Use of partitioned GMM marginal regression model with time-dependent covariates: analysis of Chinese Longitudinal Healthy Longevity Study
title_fullStr Use of partitioned GMM marginal regression model with time-dependent covariates: analysis of Chinese Longitudinal Healthy Longevity Study
title_full_unstemmed Use of partitioned GMM marginal regression model with time-dependent covariates: analysis of Chinese Longitudinal Healthy Longevity Study
title_short Use of partitioned GMM marginal regression model with time-dependent covariates: analysis of Chinese Longitudinal Healthy Longevity Study
title_sort use of partitioned gmm marginal regression model with time-dependent covariates: analysis of chinese longitudinal healthy longevity study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245823/
https://www.ncbi.nlm.nih.gov/pubmed/32448318
http://dx.doi.org/10.1186/s12874-020-01003-0
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