Cargando…

Recurrent Henoch-Schönlein Purpura with bullous rash and pulmonary nodules

BACKGROUND: Henoch-Schönlein purpura (HSP) is the most common vasculitis of childhood. It has a characteristic rash described as palpable purpura that most frequently affects the distal lower extremities and buttocks. HSP rarely presents with bullous rash nor pulmonary nodules. CASE PRESENTATION: We...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Christopher, Childers, Julie, Rabinovich, Egla, Nazareth-Pidgeon, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245848/
https://www.ncbi.nlm.nih.gov/pubmed/32448396
http://dx.doi.org/10.1186/s12969-020-00436-7
_version_ 1783537831019282432
author Zheng, Christopher
Childers, Julie
Rabinovich, Egla
Nazareth-Pidgeon, Kristina
author_facet Zheng, Christopher
Childers, Julie
Rabinovich, Egla
Nazareth-Pidgeon, Kristina
author_sort Zheng, Christopher
collection PubMed
description BACKGROUND: Henoch-Schönlein purpura (HSP) is the most common vasculitis of childhood. It has a characteristic rash described as palpable purpura that most frequently affects the distal lower extremities and buttocks. HSP rarely presents with bullous rash nor pulmonary nodules. CASE PRESENTATION: We present a novel case of a 12-years-old female with recurrent pediatric HSP with a combination of the rare manifestations of bullous rash and pulmonary nodules. She initially presented with the bullous rash, chest pain, cough, and abdominal pain. Patient was successfully treated with intravenous pulse corticosteroids followed by a high dose oral corticosteroid taper, with resolution of the bullous rash and pulmonary nodules. CONCLUSION: The rare manifestations of scarring bullous rash and pulmonary nodules can be presenting features of pediatric HSP, the combination of which has not been previously reported. The treatment of intravenous corticosteroid resolved patient’s abdominal symptoms, rash and pulmonary nodules.
format Online
Article
Text
id pubmed-7245848
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-72458482020-06-01 Recurrent Henoch-Schönlein Purpura with bullous rash and pulmonary nodules Zheng, Christopher Childers, Julie Rabinovich, Egla Nazareth-Pidgeon, Kristina Pediatr Rheumatol Online J Case Report BACKGROUND: Henoch-Schönlein purpura (HSP) is the most common vasculitis of childhood. It has a characteristic rash described as palpable purpura that most frequently affects the distal lower extremities and buttocks. HSP rarely presents with bullous rash nor pulmonary nodules. CASE PRESENTATION: We present a novel case of a 12-years-old female with recurrent pediatric HSP with a combination of the rare manifestations of bullous rash and pulmonary nodules. She initially presented with the bullous rash, chest pain, cough, and abdominal pain. Patient was successfully treated with intravenous pulse corticosteroids followed by a high dose oral corticosteroid taper, with resolution of the bullous rash and pulmonary nodules. CONCLUSION: The rare manifestations of scarring bullous rash and pulmonary nodules can be presenting features of pediatric HSP, the combination of which has not been previously reported. The treatment of intravenous corticosteroid resolved patient’s abdominal symptoms, rash and pulmonary nodules. BioMed Central 2020-05-24 /pmc/articles/PMC7245848/ /pubmed/32448396 http://dx.doi.org/10.1186/s12969-020-00436-7 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Zheng, Christopher
Childers, Julie
Rabinovich, Egla
Nazareth-Pidgeon, Kristina
Recurrent Henoch-Schönlein Purpura with bullous rash and pulmonary nodules
title Recurrent Henoch-Schönlein Purpura with bullous rash and pulmonary nodules
title_full Recurrent Henoch-Schönlein Purpura with bullous rash and pulmonary nodules
title_fullStr Recurrent Henoch-Schönlein Purpura with bullous rash and pulmonary nodules
title_full_unstemmed Recurrent Henoch-Schönlein Purpura with bullous rash and pulmonary nodules
title_short Recurrent Henoch-Schönlein Purpura with bullous rash and pulmonary nodules
title_sort recurrent henoch-schönlein purpura with bullous rash and pulmonary nodules
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245848/
https://www.ncbi.nlm.nih.gov/pubmed/32448396
http://dx.doi.org/10.1186/s12969-020-00436-7
work_keys_str_mv AT zhengchristopher recurrenthenochschonleinpurpurawithbullousrashandpulmonarynodules
AT childersjulie recurrenthenochschonleinpurpurawithbullousrashandpulmonarynodules
AT rabinovichegla recurrenthenochschonleinpurpurawithbullousrashandpulmonarynodules
AT nazarethpidgeonkristina recurrenthenochschonleinpurpurawithbullousrashandpulmonarynodules