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Frizzled related protein deficiency impairs muscle strength, gait and calpain 3 levels

BACKGROUND: Limb-girdle muscular dystrophy recessive 1 calpain3-related (LGMDR1), previously known as LGMD2A, is a disease caused by mutations in the CAPN3 gene. It is characterized by progressive weakness and muscle degeneration. Frizzled related protein (FRZB), upregulated in LGMDR1, was identifie...

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Detalles Bibliográficos
Autores principales:	Casas-Fraile, Leire, Cornelis, Frederique M., Costamagna, Domiziana, Rico, Anabel, Duelen, Robin, Sampaolesi, Maurilio M., López de Munain, Adolfo, Lories, Rik J., Sáenz, Amets
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245871/ https://www.ncbi.nlm.nih.gov/pubmed/32448375 http://dx.doi.org/10.1186/s13023-020-01372-1

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