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LRIG1 gene copy number analysis by ddPCR and correlations to clinical factors in breast cancer

BACKGROUND: Leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) copy number alterations and unbalanced gene recombination events have been reported to occur in breast cancer. Importantly, LRIG1 loss was recently shown to predict early and late relapse in stage I-II breast cancer. METHODS:...

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Detalles Bibliográficos
Autores principales: Faraz, Mahmood, Tellström, Andreas, Ardnor, Christina Edwinsdotter, Grankvist, Kjell, Huminiecki, Lukasz, Tavelin, Björn, Henriksson, Roger, Hedman, Håkan, Ljuslinder, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245921/
https://www.ncbi.nlm.nih.gov/pubmed/32448168
http://dx.doi.org/10.1186/s12885-020-06919-w