Strategies to Improve Recruitment to a De-escalation Trial: A Mixed-Methods Study of the OPTIMA Prelim Trial in Early Breast Cancer

AIMS: De-escalation trials are challenging and sometimes may fail due to poor recruitment. The OPTIMA Prelim randomised controlled trial (ISRCTN42400492) randomised patients with early stage breast cancer to chemotherapy versus ‘test-directed’ chemotherapy, with a possible outcome of no chemotherapy...

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Detalles Bibliográficos
Autores principales: Conefrey, C., Donovan, J.L., Stein, R.C., Paramasivan, S., Marshall, A., Bartlett, J., Cameron, D., Campbell, A., Dunn, J., Earl, H., Hall, P., Harmer, V., Hughes-Davies, L., Macpherson, I., Makris, A., Morgan, A., Pinder, S., Poole, C., Rea, D., Rooshenas, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: W.B. Saunders 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246331/
https://www.ncbi.nlm.nih.gov/pubmed/32089356
http://dx.doi.org/10.1016/j.clon.2020.01.029

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