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Distal Symmetric and Cardiovascular Autonomic Neuropathies in Brazilian Individuals with Type 2 Diabetes Followed in a Primary Health Care Unit: A Cross-Sectional Study
The paucity of epidemiological data regarding diabetes complications in Brazil motivated us to evaluate the prevalence rates of distal symmetric polyneuropathy (DSP) and of cardiovascular autonomic neuropathy (CAN) in individuals with type 2 diabetes (T2D) followed in a primary care unit. A total of...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246466/ https://www.ncbi.nlm.nih.gov/pubmed/32384735 http://dx.doi.org/10.3390/ijerph17093232 |
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author | Reis de Matos, Mozania Santos-Bezerra, Daniele Pereira Dias Cavalcante, Cristiane das Graças Xavier de Carvalho, Jacira Leite, Juliana Neves, Jose Antonio Januario Admoni, Sharon Nina Passarelli, Marisa Parisi, Maria Candida Correa-Giannella, Maria Lucia |
author_facet | Reis de Matos, Mozania Santos-Bezerra, Daniele Pereira Dias Cavalcante, Cristiane das Graças Xavier de Carvalho, Jacira Leite, Juliana Neves, Jose Antonio Januario Admoni, Sharon Nina Passarelli, Marisa Parisi, Maria Candida Correa-Giannella, Maria Lucia |
author_sort | Reis de Matos, Mozania |
collection | PubMed |
description | The paucity of epidemiological data regarding diabetes complications in Brazil motivated us to evaluate the prevalence rates of distal symmetric polyneuropathy (DSP) and of cardiovascular autonomic neuropathy (CAN) in individuals with type 2 diabetes (T2D) followed in a primary care unit. A total of 551 individuals (59.3% women, 65 years old; diabetes duration of 10 years; HbA1c of 7.2%, medians) were included in this cross-sectional study. DSP was diagnosed by sum of the Neuropathy Symptoms Score (NSS) and Modified Neuropathy Disability Score (NDS) and by the Semmes–Weinstein monofilament. CAN was diagnosed by cardiovascular autonomic reflex tests combined with spectral analysis of heart rate variability. The prevalence rates of DSP were 6.3% and 14.3%, as evaluated by the sum of NSS and NDS and by the Semmes–Weinstein monofilament, respectively. Those with DSP diagnosed by monofilament presented longer diabetes duration, worse glycemic control and a higher stature. The prevalence rates of incipient and definitive CAN were 12.5% and 10%, respectively. Individuals with definitive CAN presented a higher frequency of hypercholesterolemia and of arterial hypertension. The higher prevalence rate of DSP with the use of the monofilament suggests that it may be a more appropriate tool to diagnose DSP in the primary care setting in Brazil. |
format | Online Article Text |
id | pubmed-7246466 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-72464662020-06-11 Distal Symmetric and Cardiovascular Autonomic Neuropathies in Brazilian Individuals with Type 2 Diabetes Followed in a Primary Health Care Unit: A Cross-Sectional Study Reis de Matos, Mozania Santos-Bezerra, Daniele Pereira Dias Cavalcante, Cristiane das Graças Xavier de Carvalho, Jacira Leite, Juliana Neves, Jose Antonio Januario Admoni, Sharon Nina Passarelli, Marisa Parisi, Maria Candida Correa-Giannella, Maria Lucia Int J Environ Res Public Health Article The paucity of epidemiological data regarding diabetes complications in Brazil motivated us to evaluate the prevalence rates of distal symmetric polyneuropathy (DSP) and of cardiovascular autonomic neuropathy (CAN) in individuals with type 2 diabetes (T2D) followed in a primary care unit. A total of 551 individuals (59.3% women, 65 years old; diabetes duration of 10 years; HbA1c of 7.2%, medians) were included in this cross-sectional study. DSP was diagnosed by sum of the Neuropathy Symptoms Score (NSS) and Modified Neuropathy Disability Score (NDS) and by the Semmes–Weinstein monofilament. CAN was diagnosed by cardiovascular autonomic reflex tests combined with spectral analysis of heart rate variability. The prevalence rates of DSP were 6.3% and 14.3%, as evaluated by the sum of NSS and NDS and by the Semmes–Weinstein monofilament, respectively. Those with DSP diagnosed by monofilament presented longer diabetes duration, worse glycemic control and a higher stature. The prevalence rates of incipient and definitive CAN were 12.5% and 10%, respectively. Individuals with definitive CAN presented a higher frequency of hypercholesterolemia and of arterial hypertension. The higher prevalence rate of DSP with the use of the monofilament suggests that it may be a more appropriate tool to diagnose DSP in the primary care setting in Brazil. MDPI 2020-05-06 2020-05 /pmc/articles/PMC7246466/ /pubmed/32384735 http://dx.doi.org/10.3390/ijerph17093232 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Reis de Matos, Mozania Santos-Bezerra, Daniele Pereira Dias Cavalcante, Cristiane das Graças Xavier de Carvalho, Jacira Leite, Juliana Neves, Jose Antonio Januario Admoni, Sharon Nina Passarelli, Marisa Parisi, Maria Candida Correa-Giannella, Maria Lucia Distal Symmetric and Cardiovascular Autonomic Neuropathies in Brazilian Individuals with Type 2 Diabetes Followed in a Primary Health Care Unit: A Cross-Sectional Study |
title | Distal Symmetric and Cardiovascular Autonomic Neuropathies in Brazilian Individuals with Type 2 Diabetes Followed in a Primary Health Care Unit: A Cross-Sectional Study |
title_full | Distal Symmetric and Cardiovascular Autonomic Neuropathies in Brazilian Individuals with Type 2 Diabetes Followed in a Primary Health Care Unit: A Cross-Sectional Study |
title_fullStr | Distal Symmetric and Cardiovascular Autonomic Neuropathies in Brazilian Individuals with Type 2 Diabetes Followed in a Primary Health Care Unit: A Cross-Sectional Study |
title_full_unstemmed | Distal Symmetric and Cardiovascular Autonomic Neuropathies in Brazilian Individuals with Type 2 Diabetes Followed in a Primary Health Care Unit: A Cross-Sectional Study |
title_short | Distal Symmetric and Cardiovascular Autonomic Neuropathies in Brazilian Individuals with Type 2 Diabetes Followed in a Primary Health Care Unit: A Cross-Sectional Study |
title_sort | distal symmetric and cardiovascular autonomic neuropathies in brazilian individuals with type 2 diabetes followed in a primary health care unit: a cross-sectional study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246466/ https://www.ncbi.nlm.nih.gov/pubmed/32384735 http://dx.doi.org/10.3390/ijerph17093232 |
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