Cargando…

Feasibility and Tolerability of a Culture-Based Virtual Reality (VR) Training Program in Patients with Mild Cognitive Impairment: A Randomized Controlled Pilot Study

The present study examined whether a culture-based virtual reality (VR) training program is feasible and tolerable for patients with amnestic mild cognitive impairment (aMCI), and whether it could improve cognitive function in these patients. Twenty-one outpatients with aMCI were randomized to eithe...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Jong-Hwan, Liao, Yung, Kim, Du-Ri, Song, Seunghwan, Lim, Jun Ho, Park, Hyuntae, Lee, Yeanhwa, Park, Kyung Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246563/
https://www.ncbi.nlm.nih.gov/pubmed/32349413
http://dx.doi.org/10.3390/ijerph17093030
_version_ 1783537975677681664
author Park, Jong-Hwan
Liao, Yung
Kim, Du-Ri
Song, Seunghwan
Lim, Jun Ho
Park, Hyuntae
Lee, Yeanhwa
Park, Kyung Won
author_facet Park, Jong-Hwan
Liao, Yung
Kim, Du-Ri
Song, Seunghwan
Lim, Jun Ho
Park, Hyuntae
Lee, Yeanhwa
Park, Kyung Won
author_sort Park, Jong-Hwan
collection PubMed
description The present study examined whether a culture-based virtual reality (VR) training program is feasible and tolerable for patients with amnestic mild cognitive impairment (aMCI), and whether it could improve cognitive function in these patients. Twenty-one outpatients with aMCI were randomized to either the VR-based training group or the control group in a 1:1 ratio. The VR-based training group participated in training for 30 min/day, two days/week, for three months (24 times). The VR-based program was designed based on Korean traditional culture and used attention, processing speed, executive function and memory conditions to stimulate cognitive function. The adherence to the culture-based VR training program was 91.55% ± 6.41% in the VR group. The only adverse events observed in the VR group were dizziness (4.2%) and fatigue (8.3%). Analysis revealed that the VR-based training group exhibited no significant differences following the three-month VR program in Korean Mini-Mental State Examination (K-MMSE) scores, working memory functions such as performance on the digit span test, or in Stroop test performance and word fluency. We conclude that although the 12-week culture-based VR training program did not improve cognitive function, our findings revealed that the culture-based VR training program was feasible and tolerable for participants with aMCI.
format Online
Article
Text
id pubmed-7246563
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-72465632020-06-10 Feasibility and Tolerability of a Culture-Based Virtual Reality (VR) Training Program in Patients with Mild Cognitive Impairment: A Randomized Controlled Pilot Study Park, Jong-Hwan Liao, Yung Kim, Du-Ri Song, Seunghwan Lim, Jun Ho Park, Hyuntae Lee, Yeanhwa Park, Kyung Won Int J Environ Res Public Health Article The present study examined whether a culture-based virtual reality (VR) training program is feasible and tolerable for patients with amnestic mild cognitive impairment (aMCI), and whether it could improve cognitive function in these patients. Twenty-one outpatients with aMCI were randomized to either the VR-based training group or the control group in a 1:1 ratio. The VR-based training group participated in training for 30 min/day, two days/week, for three months (24 times). The VR-based program was designed based on Korean traditional culture and used attention, processing speed, executive function and memory conditions to stimulate cognitive function. The adherence to the culture-based VR training program was 91.55% ± 6.41% in the VR group. The only adverse events observed in the VR group were dizziness (4.2%) and fatigue (8.3%). Analysis revealed that the VR-based training group exhibited no significant differences following the three-month VR program in Korean Mini-Mental State Examination (K-MMSE) scores, working memory functions such as performance on the digit span test, or in Stroop test performance and word fluency. We conclude that although the 12-week culture-based VR training program did not improve cognitive function, our findings revealed that the culture-based VR training program was feasible and tolerable for participants with aMCI. MDPI 2020-04-27 2020-05 /pmc/articles/PMC7246563/ /pubmed/32349413 http://dx.doi.org/10.3390/ijerph17093030 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Park, Jong-Hwan
Liao, Yung
Kim, Du-Ri
Song, Seunghwan
Lim, Jun Ho
Park, Hyuntae
Lee, Yeanhwa
Park, Kyung Won
Feasibility and Tolerability of a Culture-Based Virtual Reality (VR) Training Program in Patients with Mild Cognitive Impairment: A Randomized Controlled Pilot Study
title Feasibility and Tolerability of a Culture-Based Virtual Reality (VR) Training Program in Patients with Mild Cognitive Impairment: A Randomized Controlled Pilot Study
title_full Feasibility and Tolerability of a Culture-Based Virtual Reality (VR) Training Program in Patients with Mild Cognitive Impairment: A Randomized Controlled Pilot Study
title_fullStr Feasibility and Tolerability of a Culture-Based Virtual Reality (VR) Training Program in Patients with Mild Cognitive Impairment: A Randomized Controlled Pilot Study
title_full_unstemmed Feasibility and Tolerability of a Culture-Based Virtual Reality (VR) Training Program in Patients with Mild Cognitive Impairment: A Randomized Controlled Pilot Study
title_short Feasibility and Tolerability of a Culture-Based Virtual Reality (VR) Training Program in Patients with Mild Cognitive Impairment: A Randomized Controlled Pilot Study
title_sort feasibility and tolerability of a culture-based virtual reality (vr) training program in patients with mild cognitive impairment: a randomized controlled pilot study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246563/
https://www.ncbi.nlm.nih.gov/pubmed/32349413
http://dx.doi.org/10.3390/ijerph17093030
work_keys_str_mv AT parkjonghwan feasibilityandtolerabilityofaculturebasedvirtualrealityvrtrainingprograminpatientswithmildcognitiveimpairmentarandomizedcontrolledpilotstudy
AT liaoyung feasibilityandtolerabilityofaculturebasedvirtualrealityvrtrainingprograminpatientswithmildcognitiveimpairmentarandomizedcontrolledpilotstudy
AT kimduri feasibilityandtolerabilityofaculturebasedvirtualrealityvrtrainingprograminpatientswithmildcognitiveimpairmentarandomizedcontrolledpilotstudy
AT songseunghwan feasibilityandtolerabilityofaculturebasedvirtualrealityvrtrainingprograminpatientswithmildcognitiveimpairmentarandomizedcontrolledpilotstudy
AT limjunho feasibilityandtolerabilityofaculturebasedvirtualrealityvrtrainingprograminpatientswithmildcognitiveimpairmentarandomizedcontrolledpilotstudy
AT parkhyuntae feasibilityandtolerabilityofaculturebasedvirtualrealityvrtrainingprograminpatientswithmildcognitiveimpairmentarandomizedcontrolledpilotstudy
AT leeyeanhwa feasibilityandtolerabilityofaculturebasedvirtualrealityvrtrainingprograminpatientswithmildcognitiveimpairmentarandomizedcontrolledpilotstudy
AT parkkyungwon feasibilityandtolerabilityofaculturebasedvirtualrealityvrtrainingprograminpatientswithmildcognitiveimpairmentarandomizedcontrolledpilotstudy