Designing Single-Molecule Magnets as Drugs with Dual Anti-Inflammatory and Anti-Diabetic Effects

We have designed and synthesized two novel cobalt coordination compounds using bumetanide (bum) and indomethacin (ind) therapeutic agents. The anti-inflammatory effects of cobalt metal complexes with ind and bum were assayed in lipopolysaccharide stimulated RAW 264.7 macrophages by inhibition of nit...

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Detalles Bibliográficos
Autores principales: Navas, Arturo, Jannus, Fatin, Fernández, Belén, Cepeda, Javier, Medina O’Donnell, Marta, Díaz-Ruiz, Luis, Sánchez-González, Cristina, Llopis, Juan, Seco, José M., Rufino-Palomares, E., Lupiáñez, José Antonio, Gómez-Ruiz, Santiago, Quiles, José Luis, Battino, Maurizio, Choquesillo-Lazarte, Duane, Ruiz-Muelle, Ana Belén, Fernández, Ignacio, Reyes-Zurita, Fernando, Rodríguez-Diéguez, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246571/
https://www.ncbi.nlm.nih.gov/pubmed/32365648
http://dx.doi.org/10.3390/ijms21093146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246571/
https://www.ncbi.nlm.nih.gov/pubmed/32365648
http://dx.doi.org/10.3390/ijms21093146

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