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Heterogeneity of Integrin α(IIb)β(3) Function in Pediatric Immune Thrombocytopenia Revealed by Continuous Flow Cytometry Analysis

Immune thrombocytopenia (ITP) is an autoimmune condition primarily induced by the loss of immune tolerance to the platelet glycoproteins. Here we develop a novel flow cytometry approach to analyze integrin α(IIb)β(3) functioning in ITP in comparison with Glanzmann thrombasthenia (GT) (negative contr...

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Detalles Bibliográficos
Autores principales: Martyanov, Alexey A., Morozova, Daria S., Sorokina, Maria A., Filkova, Aleksandra A., Fedorova, Daria V., Uzueva, Selima S., Suntsova, Elena V., Novichkova, Galina A., Zharkov, Pavel A., Panteleev, Mikhail A., Sveshnikova, Anastasia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246588/
https://www.ncbi.nlm.nih.gov/pubmed/32344835
http://dx.doi.org/10.3390/ijms21093035