Cargando…

Effect of Particulate Matter Exposure on Respiratory Health of e-Waste Workers at Agbogbloshie, Accra, Ghana

Background: Direct and continuous exposure to particulate matter (PM), especially in occupational settings is known to impact negatively on respiratory health and lung function. Objective: To determine the association between concentrations of PM (2.5, 2.5–10 and 10 µm) in breathing zone and lung fu...

Descripción completa

Detalles Bibliográficos
Autores principales: Amoabeng Nti, Afua Asabea, Arko-Mensah, John, Botwe, Paul K., Dwomoh, Duah, Kwarteng, Lawrencia, Takyi, Sylvia Akpene, Acquah, Augustine Appah, Tettey, Prudence, Basu, Niladri, Batterman, Stuart, Robins, Thomas G., Fobil, Julius N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246629/
https://www.ncbi.nlm.nih.gov/pubmed/32349371
http://dx.doi.org/10.3390/ijerph17093042
_version_ 1783537991105380352
author Amoabeng Nti, Afua Asabea
Arko-Mensah, John
Botwe, Paul K.
Dwomoh, Duah
Kwarteng, Lawrencia
Takyi, Sylvia Akpene
Acquah, Augustine Appah
Tettey, Prudence
Basu, Niladri
Batterman, Stuart
Robins, Thomas G.
Fobil, Julius N.
author_facet Amoabeng Nti, Afua Asabea
Arko-Mensah, John
Botwe, Paul K.
Dwomoh, Duah
Kwarteng, Lawrencia
Takyi, Sylvia Akpene
Acquah, Augustine Appah
Tettey, Prudence
Basu, Niladri
Batterman, Stuart
Robins, Thomas G.
Fobil, Julius N.
author_sort Amoabeng Nti, Afua Asabea
collection PubMed
description Background: Direct and continuous exposure to particulate matter (PM), especially in occupational settings is known to impact negatively on respiratory health and lung function. Objective: To determine the association between concentrations of PM (2.5, 2.5–10 and 10 µm) in breathing zone and lung function of informal e-waste workers at Agbogbloshie. Methods: To evaluate lung function responses to PM (2.5, 2.5–10 and 10 µm), we conducted a longitudinal cohort study with three repeated measures among 207 participants comprising 142 healthy e-waste workers from Agbogbloshie scrapyard and 65 control participants from Madina-Zongo in Accra, Ghana from 2017–2018. Lung function parameters (FVC, FEV1, FEV1/FVC, PEF, and FEF 25-75) and PM (2.5, 2.5–10 and 10 µm) concentrations were measured, corresponding to prevailing seasonal variations. Socio-demographic data, respiratory exposures and lifestyle habits were determined using questionnaires. Random effects models were then used to examine the effects of PM (2.5, 2.5–10 and 10 µm) on lung function. Results: The median concentrations of PM (2.5, 2.5–10 and 10 µm) were all consistently above the WHO ambient air standards across the study waves. Small effect estimates per IQR of PM (2.5, 2.5–10 and 10 µm) on lung function parameters were observed even after adjustment for potential confounders. However, a 10 µg increase in PM (2.5, 2.5–10 and 10 µm) was associated with decreases in PEF and FEF 25–75 by 13.3% % [β = −3.133; 95% CI: −0.243, −0.022) and 26.6% [β = −0.266; 95% CI: −0.437, 0.094]. E-waste burning and a history of asthma significantly predicted a decrease in PEF by 14.2% [β = −0.142; 95% CI: −0.278, −0.008) and FEV1 by 35.8% [β = −0.358; 95% CI: −0.590, 0.125] among e-waste burners. Conclusions: Direct exposure of e-waste workers to PM predisposes to decline in lung function and risk for small airway diseases such as asthma and COPD.
format Online
Article
Text
id pubmed-7246629
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-72466292020-06-10 Effect of Particulate Matter Exposure on Respiratory Health of e-Waste Workers at Agbogbloshie, Accra, Ghana Amoabeng Nti, Afua Asabea Arko-Mensah, John Botwe, Paul K. Dwomoh, Duah Kwarteng, Lawrencia Takyi, Sylvia Akpene Acquah, Augustine Appah Tettey, Prudence Basu, Niladri Batterman, Stuart Robins, Thomas G. Fobil, Julius N. Int J Environ Res Public Health Article Background: Direct and continuous exposure to particulate matter (PM), especially in occupational settings is known to impact negatively on respiratory health and lung function. Objective: To determine the association between concentrations of PM (2.5, 2.5–10 and 10 µm) in breathing zone and lung function of informal e-waste workers at Agbogbloshie. Methods: To evaluate lung function responses to PM (2.5, 2.5–10 and 10 µm), we conducted a longitudinal cohort study with three repeated measures among 207 participants comprising 142 healthy e-waste workers from Agbogbloshie scrapyard and 65 control participants from Madina-Zongo in Accra, Ghana from 2017–2018. Lung function parameters (FVC, FEV1, FEV1/FVC, PEF, and FEF 25-75) and PM (2.5, 2.5–10 and 10 µm) concentrations were measured, corresponding to prevailing seasonal variations. Socio-demographic data, respiratory exposures and lifestyle habits were determined using questionnaires. Random effects models were then used to examine the effects of PM (2.5, 2.5–10 and 10 µm) on lung function. Results: The median concentrations of PM (2.5, 2.5–10 and 10 µm) were all consistently above the WHO ambient air standards across the study waves. Small effect estimates per IQR of PM (2.5, 2.5–10 and 10 µm) on lung function parameters were observed even after adjustment for potential confounders. However, a 10 µg increase in PM (2.5, 2.5–10 and 10 µm) was associated with decreases in PEF and FEF 25–75 by 13.3% % [β = −3.133; 95% CI: −0.243, −0.022) and 26.6% [β = −0.266; 95% CI: −0.437, 0.094]. E-waste burning and a history of asthma significantly predicted a decrease in PEF by 14.2% [β = −0.142; 95% CI: −0.278, −0.008) and FEV1 by 35.8% [β = −0.358; 95% CI: −0.590, 0.125] among e-waste burners. Conclusions: Direct exposure of e-waste workers to PM predisposes to decline in lung function and risk for small airway diseases such as asthma and COPD. MDPI 2020-04-27 2020-05 /pmc/articles/PMC7246629/ /pubmed/32349371 http://dx.doi.org/10.3390/ijerph17093042 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Amoabeng Nti, Afua Asabea
Arko-Mensah, John
Botwe, Paul K.
Dwomoh, Duah
Kwarteng, Lawrencia
Takyi, Sylvia Akpene
Acquah, Augustine Appah
Tettey, Prudence
Basu, Niladri
Batterman, Stuart
Robins, Thomas G.
Fobil, Julius N.
Effect of Particulate Matter Exposure on Respiratory Health of e-Waste Workers at Agbogbloshie, Accra, Ghana
title Effect of Particulate Matter Exposure on Respiratory Health of e-Waste Workers at Agbogbloshie, Accra, Ghana
title_full Effect of Particulate Matter Exposure on Respiratory Health of e-Waste Workers at Agbogbloshie, Accra, Ghana
title_fullStr Effect of Particulate Matter Exposure on Respiratory Health of e-Waste Workers at Agbogbloshie, Accra, Ghana
title_full_unstemmed Effect of Particulate Matter Exposure on Respiratory Health of e-Waste Workers at Agbogbloshie, Accra, Ghana
title_short Effect of Particulate Matter Exposure on Respiratory Health of e-Waste Workers at Agbogbloshie, Accra, Ghana
title_sort effect of particulate matter exposure on respiratory health of e-waste workers at agbogbloshie, accra, ghana
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246629/
https://www.ncbi.nlm.nih.gov/pubmed/32349371
http://dx.doi.org/10.3390/ijerph17093042
work_keys_str_mv AT amoabengntiafuaasabea effectofparticulatematterexposureonrespiratoryhealthofewasteworkersatagbogbloshieaccraghana
AT arkomensahjohn effectofparticulatematterexposureonrespiratoryhealthofewasteworkersatagbogbloshieaccraghana
AT botwepaulk effectofparticulatematterexposureonrespiratoryhealthofewasteworkersatagbogbloshieaccraghana
AT dwomohduah effectofparticulatematterexposureonrespiratoryhealthofewasteworkersatagbogbloshieaccraghana
AT kwartenglawrencia effectofparticulatematterexposureonrespiratoryhealthofewasteworkersatagbogbloshieaccraghana
AT takyisylviaakpene effectofparticulatematterexposureonrespiratoryhealthofewasteworkersatagbogbloshieaccraghana
AT acquahaugustineappah effectofparticulatematterexposureonrespiratoryhealthofewasteworkersatagbogbloshieaccraghana
AT tetteyprudence effectofparticulatematterexposureonrespiratoryhealthofewasteworkersatagbogbloshieaccraghana
AT basuniladri effectofparticulatematterexposureonrespiratoryhealthofewasteworkersatagbogbloshieaccraghana
AT battermanstuart effectofparticulatematterexposureonrespiratoryhealthofewasteworkersatagbogbloshieaccraghana
AT robinsthomasg effectofparticulatematterexposureonrespiratoryhealthofewasteworkersatagbogbloshieaccraghana
AT fobiljuliusn effectofparticulatematterexposureonrespiratoryhealthofewasteworkersatagbogbloshieaccraghana