Feasibility of Imaging EpCAM Expression in Ovarian Cancer Using Radiolabeled DARPin Ec1

Epithelial cell adhesion molecule (EpCAM) is overexpressed in 55%–75% of ovarian carcinomas (OC). EpCAM might be used as a target for a treatment of disseminated OC. Designed ankyrin repeats protein (DARPin) Ec1 is a small (18 kDa) protein, which binds to EpCAM with subnanomolar affinity. We tested...

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Detalles Bibliográficos
Autores principales: Vorobyeva, Anzhelika, Konovalova, Elena, Xu, Tianqi, Schulga, Alexey, Altai, Mohamed, Garousi, Javad, Rinne, Sara S., Orlova, Anna, Tolmachev, Vladimir, Deyev, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246691/
https://www.ncbi.nlm.nih.gov/pubmed/32392820
http://dx.doi.org/10.3390/ijms21093310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246691/
https://www.ncbi.nlm.nih.gov/pubmed/32392820
http://dx.doi.org/10.3390/ijms21093310

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