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Hand Sanitizers: A Review on Formulation Aspects, Adverse Effects, and Regulations
Hand hygiene is of utmost importance as it may be contaminated easily from direct contact with airborne microorganism droplets from coughs and sneezes. Particularly in situations like pandemic outbreak, it is crucial to interrupt the transmission chain of the virus by the practice of proper hand san...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246736/ https://www.ncbi.nlm.nih.gov/pubmed/32403261 http://dx.doi.org/10.3390/ijerph17093326 |
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author | Jing, Jane Lee Jia Pei Yi, Thong Bose, Rajendran J. C. McCarthy, Jason R. Tharmalingam, Nagendran Madheswaran, Thiagarajan |
author_facet | Jing, Jane Lee Jia Pei Yi, Thong Bose, Rajendran J. C. McCarthy, Jason R. Tharmalingam, Nagendran Madheswaran, Thiagarajan |
author_sort | Jing, Jane Lee Jia |
collection | PubMed |
description | Hand hygiene is of utmost importance as it may be contaminated easily from direct contact with airborne microorganism droplets from coughs and sneezes. Particularly in situations like pandemic outbreak, it is crucial to interrupt the transmission chain of the virus by the practice of proper hand sanitization. It can be achieved with contact isolation and strict infection control tool like maintaining good hand hygiene in hospital settings and in public. The success of the hand sanitization solely depends on the use of effective hand disinfecting agents formulated in various types and forms such as antimicrobial soaps, water-based or alcohol-based hand sanitizer, with the latter being widely used in hospital settings. To date, most of the effective hand sanitizer products are alcohol-based formulations containing 62%–95% of alcohol as it can denature the proteins of microbes and the ability to inactivate viruses. This systematic review correlated with the data available in Pubmed, and it will investigate the range of available hand sanitizers and their effectiveness as well as the formulation aspects, adverse effects, and recommendations to enhance the formulation efficiency and safety. Further, this article highlights the efficacy of alcohol-based hand sanitizer against the coronavirus. |
format | Online Article Text |
id | pubmed-7246736 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-72467362020-06-10 Hand Sanitizers: A Review on Formulation Aspects, Adverse Effects, and Regulations Jing, Jane Lee Jia Pei Yi, Thong Bose, Rajendran J. C. McCarthy, Jason R. Tharmalingam, Nagendran Madheswaran, Thiagarajan Int J Environ Res Public Health Review Hand hygiene is of utmost importance as it may be contaminated easily from direct contact with airborne microorganism droplets from coughs and sneezes. Particularly in situations like pandemic outbreak, it is crucial to interrupt the transmission chain of the virus by the practice of proper hand sanitization. It can be achieved with contact isolation and strict infection control tool like maintaining good hand hygiene in hospital settings and in public. The success of the hand sanitization solely depends on the use of effective hand disinfecting agents formulated in various types and forms such as antimicrobial soaps, water-based or alcohol-based hand sanitizer, with the latter being widely used in hospital settings. To date, most of the effective hand sanitizer products are alcohol-based formulations containing 62%–95% of alcohol as it can denature the proteins of microbes and the ability to inactivate viruses. This systematic review correlated with the data available in Pubmed, and it will investigate the range of available hand sanitizers and their effectiveness as well as the formulation aspects, adverse effects, and recommendations to enhance the formulation efficiency and safety. Further, this article highlights the efficacy of alcohol-based hand sanitizer against the coronavirus. MDPI 2020-05-11 2020-05 /pmc/articles/PMC7246736/ /pubmed/32403261 http://dx.doi.org/10.3390/ijerph17093326 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Jing, Jane Lee Jia Pei Yi, Thong Bose, Rajendran J. C. McCarthy, Jason R. Tharmalingam, Nagendran Madheswaran, Thiagarajan Hand Sanitizers: A Review on Formulation Aspects, Adverse Effects, and Regulations |
title | Hand Sanitizers: A Review on Formulation Aspects, Adverse Effects, and Regulations |
title_full | Hand Sanitizers: A Review on Formulation Aspects, Adverse Effects, and Regulations |
title_fullStr | Hand Sanitizers: A Review on Formulation Aspects, Adverse Effects, and Regulations |
title_full_unstemmed | Hand Sanitizers: A Review on Formulation Aspects, Adverse Effects, and Regulations |
title_short | Hand Sanitizers: A Review on Formulation Aspects, Adverse Effects, and Regulations |
title_sort | hand sanitizers: a review on formulation aspects, adverse effects, and regulations |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246736/ https://www.ncbi.nlm.nih.gov/pubmed/32403261 http://dx.doi.org/10.3390/ijerph17093326 |
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