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Pathogenic Roles of Autoantibodies and Aberrant Epigenetic Regulation of Immune and Connective Tissue Cells in the Tissue Fibrosis of Patients with Systemic Sclerosis

Systemic sclerosis (SSc) is a multi-system autoimmune disease with tissue fibrosis prominent in the skin and lung. In this review, we briefly describe the autoimmune features (mainly autoantibody production and cytokine profiles) and the potential pathogenic contributors including genetic/epigenetic...

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Detalles Bibliográficos
Autores principales: Tsai, Chang-Youh, Hsieh, Song-Chou, Wu, Tsai-Hung, Li, Ko-Jen, Shen, Chieh-Yu, Liao, Hsien-Tzung, Wu, Cheng-Han, Kuo, Yu-Min, Lu, Cheng-Shiun, Yu, Chia-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246753/
https://www.ncbi.nlm.nih.gov/pubmed/32349208
http://dx.doi.org/10.3390/ijms21093069