Cargando…

Restoring Mitochondrial Function While Avoiding Redox Stress: The Key to Preventing Ischemia/Reperfusion Injury in Machine Perfused Liver Grafts?

Mitochondria sense changes resulting from the ischemia and subsequent reperfusion of an organ and mitochondrial reactive oxygen species (ROS) production initiates a series of events, which over time result in the development of full-fledged ischemia-reperfusion injury (IRI), severely affecting graft...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hofmann, Julia, Otarashvili, Giorgi, Meszaros, Andras, Ebner, Susanne, Weissenbacher, Annemarie, Cardini, Benno, Oberhuber, Rupert, Resch, Thomas, Öfner, Dietmar, Schneeberger, Stefan, Troppmair, Jakob, Hautz, Theresa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246795/ https://www.ncbi.nlm.nih.gov/pubmed/32365506 http://dx.doi.org/10.3390/ijms21093132

Ejemplares similares

Ex Vivo Mesenchymal Stem Cell Therapy to Regenerate Machine Perfused Organs
por: Bogensperger, Christina, et al.
Publicado: (2021)

Dealing With Liver Transplantation during Coronavirus Disease 2019 Pandemic: Normothermic Machine Perfusion Enables for Donor, Organ, and Recipient Assessment: A Case Report
por: Bogensperger, Christina, et al.
Publicado: (2020)

Mitochondrial respiration during normothermic liver machine perfusion predicts clinical outcome
por: Meszaros, Andras T., et al.
Publicado: (2022)

Hyperspectral Imaging as a Tool for Viability Assessment During Normothermic Machine Perfusion of Human Livers: A Proof of Concept Pilot Study
por: Fodor, Margot, et al.
Publicado: (2022)

Bioenergetic and Cytokine Profiling May Help to Rescue More DCD Livers for Transplantation
por: Hofmann, Julia, et al.
Publicado: (2023)

Transplanting Marginal Organs in the Era of Modern Machine Perfusion and Advanced Organ Monitoring
por: Resch, Thomas, et al.
Publicado: (2020)

Immune cell dynamics deconvoluted by single-cell RNA sequencing in normothermic machine perfusion of the liver
por: Hautz, T., et al.
Publicado: (2023)

Post-Transplant Malignancies following Pancreas Transplantation: Incidence and Implications on Long-Term Outcome from a Single-Center Perspective
por: Krendl, Felix J., et al.
Publicado: (2021)

Cell-Based Regeneration and Treatment of Liver Diseases
por: Hofmann, Julia, et al.
Publicado: (2021)

Novel, Innovative Models to Study Ischemia/Reperfusion-Related Redox Damage in Organ Transplantation
por: Hofmann, Julia, et al.
Publicado: (2022)

A Retrospective Propensity Score Matched Analysis Reveals Superiority of Hypothermic Machine Perfusion over Static Cold Storage in Deceased Donor Kidney Transplantation
por: Gasteiger, Silvia, et al.
Publicado: (2020)

Reassessment of Relevance and Predictive Value of Parameters Indicating Early Graft Dysfunction in Liver Transplantation: AST Is a Weak, but Bilirubin and INR Strong Predictors of Mortality
por: Fodor, Margot, et al.
Publicado: (2021)

Liver Transplantation in Recipients With a Positive Crossmatch: A Retrospective Single-Center Match-Pair Analysis
por: Krendl, Felix J., et al.
Publicado: (2023)

Lymphocytes as an Indicator for Initial Kidney Function: A Single Center Analysis of Outcome after Alemtuzumab or Basiliximab Induction
por: Weissenbacher, Annemarie, et al.
Publicado: (2015)

Hyperspectral Imaging and Machine Perfusion in Solid Organ Transplantation: Clinical Potentials of Combining Two Novel Technologies
por: Fodor, Margot, et al.
Publicado: (2021)

Single Center, Propensity Score Matching Analysis of Different Reconstruction Techniques following Pancreatoduodenectomy
por: Bellotti, Ruben, et al.
Publicado: (2023)

48 h Normothermic Machine Perfusion With Urine Recirculation for Discarded Human Kidney Grafts
por: Messner, Franka, et al.
Publicado: (2023)

Surgical techniques and strategies for the treatment of primary liver tumours: hepatocellular and cholangiocellular carcinoma
por: Braunwarth, Eva, et al.
Publicado: (2018)

Perioperative Perfusion of Allografts with Anti-Human T-lymphocyte Globulin Does Not Improve Outcome Post Liver Transplantation—A Randomized Placebo-Controlled Trial
por: Ritschl, Paul Viktor, et al.
Publicado: (2021)

Indications for liver surgery in benign tumours
por: Fodor, Margot, et al.
Publicado: (2018)

Sodium Sulfite Exacerbates Allograft Vasculopathy and Affects Tryptophan Breakdown in Murine Heterotopic Aortic Transplantation
por: Sucher, Robert, et al.
Publicado: (2019)

Myogenic progenitor cell transplantation for muscle regeneration following hindlimb ischemia and reperfusion
por: Messner, Franka, et al.
Publicado: (2021)

Forty‐eight hours of normothermic kidney preservation applying urine recirculation
por: Weissenbacher, Annemarie, et al.
Publicado: (2022)

Sex matching does not impact the outcome after simultaneous pancreas‐kidney transplantation
por: Messner, Franka, et al.
Publicado: (2019)

Graft Pre-conditioning by Peri-Operative Perfusion of Kidney Allografts With Rabbit Anti-human T-lymphocyte Globulin Results in Improved Kidney Graft Function in the Early Post-transplantation Period—a Prospective, Randomized Placebo-Controlled Trial
por: Ritschl, Paul V., et al.
Publicado: (2018)

Subcutaneous administration of a neutralizing IL‐1β antibody prolongs limb allograft survival
por: Hautz, Theresa, et al.
Publicado: (2018)

The liver-resident immune cell repertoire - A boon or a bane during machine perfusion?
por: Fodor, M., et al.
Publicado: (2022)

Intraductal tubulopapillary neoplasm (ITPN) of the pancreas associated with an invasive component: a case report with review of the literature
por: Kuscher, Stefanie, et al.
Publicado: (2017)

Liver Transplantation Activity in the Eurotransplant Area Is Recovering Slowly During the COVID-19 Crisis
por: Putzer, Gabriel, et al.
Publicado: (2020)

Good Long-term Results Following Simultaneous Pancreas-kidney Transplantation in a 69-y-old Recipient: A Case Report
por: Bösmüller, Claudia, et al.
Publicado: (2021)

Mouse Model for Pancreas Transplantation Using a Modified Cuff Technique
por: Cardini, Benno, et al.
Publicado: (2017)

Good Results with Individually Adapted Long-Term Immunosuppression Following Alemtuzumab Versus ATG Induction Therapy in Combined Kidney-Pancreas Transplantation: A Single-Center Report
por: Bösmüller, Claudia, et al.
Publicado: (2019)

Integrating interventional oncology in the treatment of liver tumors
por: Putzer, D., et al.
Publicado: (2018)

The Role of BRAF in Metastatic Colorectal Carcinoma–Past, Present, and Future
por: Djanani, Angela, et al.
Publicado: (2020)

Differential depletion of total T cells and regulatory T cells and prolonged allotransplant survival in CD3Ɛ humanized mice treated with polyclonal anti human thymocyte globulin
por: Buszko, Maja, et al.
Publicado: (2017)

Successful management of recurrent focal segmental glomerulosclerosis
por: Kienzl‐Wagner, Katrin, et al.
Publicado: (2018)

Outcomes of pancreas retransplantation in patients with pancreas graft failure
por: Gasteiger, S., et al.
Publicado: (2018)

Rotational Transport of Islets: The Best Way for Islets to Get around?
por: Oberhuber, Rupert, et al.
Publicado: (2013)

Long‐term outcome after hand and forearm transplantation – a retrospective study
por: Hautz, Theresa, et al.
Publicado: (2020)

Editorial: Immunology of machine perfused organs and tissues
por: Hautz, Theresa, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_snqoc8ofhecrvp73gih6cb8bo2