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Whole Genome DNA Methylation Analysis of Active Pulmonary Tuberculosis Disease Identifies Novel Epigenotypes: PARP9/miR-505/RASGRP4/GNG12 Gene Methylation and Clinical Phenotypes

We hypothesized that DNA methylation patterns may contribute to the development of active pulmonary tuberculosis (TB). Illumina’s DNA methylation 450 K assay was used to identify differentially methylated loci (DML) in a discovery cohort of 12 active pulmonary TB patients and 6 healthy subjects (HS)...

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Detalles Bibliográficos
Autores principales:	Chen, Yung-Che, Hsiao, Chang-Chun, Chen, Ting-Wen, Wu, Chao-Chien, Chao, Tung-Ying, Leung, Sum-Yee, Eng, Hock-Liew, Lee, Chiu-Ping, Wang, Ting-Ya, Lin, Meng-Chih
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246806/ https://www.ncbi.nlm.nih.gov/pubmed/32365959 http://dx.doi.org/10.3390/ijms21093180

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