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Protein Arginine Methyltransferase 1 (PRMT1) Selective Inhibitor, TC-E 5003, Has Anti-Inflammatory Properties in TLR4 Signaling

Protein arginine methyltransferase 1 (PRMT1) is the most predominant PRMT and is type I, meaning it generates monomethylarginine and asymmetric dimethylarginine. PRMT1 has functions in oxidative stress, inflammation and cancers, and modulates diverse diseases; consequently, numerous trials to develo...

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Detalles Bibliográficos
Autores principales: Kim, Eunji, Jang, Jiwon, Park, Jae Gwang, Kim, Kyung-Hee, Yoon, Keejung, Yoo, Byong Chul, Cho, Jae Youl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246892/
https://www.ncbi.nlm.nih.gov/pubmed/32357521
http://dx.doi.org/10.3390/ijms21093058