Limited Proteolysis of Cyclooxygenase-2 Enhances Cell Proliferation

Accumulating evidence suggests that the cyclooxygenase-2 (COX-2) enzyme has additional catalytic-independent functions. Here we show that COX-2 appears to be cleaved in mouse and human tumors, which led us to hypothesize that COX-2 proteolysis may play a role in cell proliferation. The data presente...

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Detalles Bibliográficos
Autores principales: Saadi, Esraa, Sood, Rapita, Dromi, Ido, Srouji, Ranin, Abu Hatoum, Ossama, Tal, Sharon, Barki-Harrington, Liza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246915/
https://www.ncbi.nlm.nih.gov/pubmed/32366045
http://dx.doi.org/10.3390/ijms21093195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246915/
https://www.ncbi.nlm.nih.gov/pubmed/32366045
http://dx.doi.org/10.3390/ijms21093195

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