Cargando…

Effects of PDE3 Inhibitor Olprinone on the Respiratory Parameters, Inflammation, and Apoptosis in an Experimental Model of Acute Respiratory Distress Syndrome

This study aimed to investigate whether a selective phosphodiesterase-3 (PDE3) inhibitor olprinone can positively influence the inflammation, apoptosis, and respiratory parameters in animals with acute respiratory distress syndrome (ARDS) model induced by repetitive saline lung lavage. Adult rabbits...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kosutova, Petra, Mikolka, Pavol, Balentova, Sona, Adamkov, Marian, Calkovska, Andrea, Mokra, Daniela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247002/ https://www.ncbi.nlm.nih.gov/pubmed/32403267 http://dx.doi.org/10.3390/ijms21093382

Ejemplares similares

Anti-inflammatory activity of non-selective PDE inhibitor aminophylline on the lung tissue and respiratory parameters in animal model of ARDS
por: Kosutova, Petra, et al.
Publicado: (2023)

N-Acetylcysteine in Mechanically Ventilated Rats with Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome: The Effect of Intravenous Dose on Oxidative Damage and Inflammation
por: Kolomaznik, Maros, et al.
Publicado: (2021)

Nitric-Oxide-Releasing Dexamethasone Derivative NCX-1005 Improves Lung Function and Attenuates Inflammation in Experimental Lavage-Induced ARDS
por: Kosutova, Petra, et al.
Publicado: (2021)

Time-Dependent Oxidative Alterations in Plasma and Lung Tissue after Meconium Aspiration in a Rabbit Model
por: Kosutova, Petra, et al.
Publicado: (2022)

Recombinant Human Superoxide Dismutase and N-Acetylcysteine Addition to Exogenous Surfactant in the Treatment of Meconium Aspiration Syndrome
por: Kopincova, Jana, et al.
Publicado: (2019)

Corticosteroids in Acute Lung Injury: The Dilemma Continues
por: Mokra, Daniela, et al.
Publicado: (2019)

Effects of Green Tea Polyphenol Epigallocatechin-3-Gallate on Markers of Inflammation and Fibrosis in a Rat Model of Pulmonary Silicosis
por: Adamcakova, Jana, et al.
Publicado: (2023)

The Effect of Modified Porcine Surfactant Alone or in Combination with Polymyxin B on Lung Homeostasis in LPS-Challenged and Mechanically Ventilated Adult Rats
por: Kolomaznik, Maros, et al.
Publicado: (2020)

Molecular, Cellular and Functional Effects of Radiation-Induced Brain Injury: A Review
por: Balentova, Sona, et al.
Publicado: (2015)

Olprinone Attenuates the Acute Inflammatory Response and Apoptosis after Spinal Cord Trauma in Mice
por: Esposito, Emanuela, et al.
Publicado: (2010)

Population pharmacokinetics of olprinone in healthy male volunteers
por: Kunisawa, Takayuki, et al.
Publicado: (2014)

Impact of synthetic surfactant CHF5633 with SP‐B and SP‐C analogues on lung function and inflammation in rabbit model of acute respiratory distress syndrome
por: Mikolka, Pavol, et al.
Publicado: (2021)

Lung surfactant alterations in pulmonary thromboembolism
por: Calkovska, A, et al.
Publicado: (2009)

Advances in the Use of N-Acetylcysteine in Chronic Respiratory Diseases
por: Mokra, Daniela, et al.
Publicado: (2023)

The Common Haplotype GATGACA in Surfactant-Protein B Gene Is Protective for Respiratory Distress Syndrome in Preterm Neonates
por: Mikolajcikova, Silvia, et al.
Publicado: (2022)

Synthetic surfactant with a recombinant surfactant protein C analogue improves lung function and attenuates inflammation in a model of acute respiratory distress syndrome in adult rabbits
por: Zebialowicz Ahlström, J., et al.
Publicado: (2019)

Green Tea Polyphenol (-)-Epigallocatechin-3-Gallate (EGCG): A Time for a New Player in the Treatment of Respiratory Diseases?
por: Mokra, Daniela, et al.
Publicado: (2022)

Therapeutic Effects of Green Tea Polyphenol (‒)-Epigallocatechin-3-Gallate (EGCG) in Relation to Molecular Pathways Controlling Inflammation, Oxidative Stress, and Apoptosis
por: Mokra, Daniela, et al.
Publicado: (2022)

Inhaled Phosphodiesterase 4 (PDE4) Inhibitors for Inflammatory Respiratory Diseases
por: Phillips, Jonathan E.
Publicado: (2020)

Inhibitory effect of PDE2 on inflammation and apoptosis in cerebral ischemia-reperfusion injury
por: Wan, Ding, et al.
Publicado: (2022)

Intrapartum Respiratory Distress
por: Shaw, S.W. Steven
Publicado: (2017)

Intrapartum Respiratory Distress
por: Shaw, S.W. Steven
Publicado: (2017)

Acute Respiratory Distress
por: Maloy, James, et al.
Publicado: (2018)

Woman in respiratory distress
por: Frantz, Eric, et al.
Publicado: (2021)

Ibudilast, a Phosphodiesterase-4 Inhibitor, Ameliorates Acute Respiratory Distress Syndrome in Neonatal Mice by Alleviating Inflammation and Apoptosis
por: Yang, Dongjie, et al.
Publicado: (2020)

Magnesium Hydride Ameliorates Endotoxin-Induced Acute Respiratory Distress Syndrome by Inhibiting Inflammation, Oxidative Stress, and Cell Apoptosis
por: Shi, Xuan, et al.
Publicado: (2022)

Unique patterns of lower respiratory tract microbiota are associated with inflammation and hospital mortality in acute respiratory distress syndrome
por: Kyo, Michihito, et al.
Publicado: (2019)

Relevance of granulocyte apoptosis to resolution of inflammation at the respiratory mucosa
por: Leitch, A E, et al.
Publicado: (2008)

Differential Expression and Function of PDE8 and PDE4 in Effector T cells: Implications for PDE8 as a Drug Target in Inflammation
por: Vang, Amanda G., et al.
Publicado: (2016)

Acute respiratory distress syndrome.
por: Lunn, J. J., et al.
Publicado: (1998)

The adult respiratory distress syndrome.
por: Biondi, J. W., et al.
Publicado: (1986)

Acute respiratory distress syndrome
por: Matthay, Michael A., et al.
Publicado: (2019)

An unusual cause of respiratory distress
por: Rajagopala, S, et al.
Publicado: (2019)

Acute respiratory distress syndrome
por: Chen, Hsing I., et al.
Publicado: (2003)

Acute Respiratory Distress Syndrome
por: Ahmad, Fawaz, et al.
Publicado: (2018)

Acute respiratory distress syndrome
por: Sweeney, Rob Mac, et al.
Publicado: (2016)

An elderly woman with respiratory distress
por: Ullo, Michael, et al.
Publicado: (2020)

Acute Respiratory Distress Syndrome
por: Gragossian, Alin, et al.
Publicado: (2022)

Acute Respiratory Distress Syndrome
por: Adams, Claire E., et al.
Publicado: (2022)

Acute respiratory distress syndrome
por: Meyer, Nuala J, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_jg9o934g71lfcvkp1c647kde7t