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Methotrexate use and NAD(+)/NADH metabolism in psoriatic keratinocytes

Methotrexate inhibits tetrahydrofolic acid production and influences mitochondrial oxygen uptake and activity of several enzymes in the respiratory chain reactions, which utilize nicotinamide adenine dinucleotide-linked (NAD-linked) substrates. Hyperproliferation of keratinocytes in psoriasis requir...

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Detalles Bibliográficos
Autores principales:	Liszewska, Agata, Robak, Ewa, Bernacka, Małgorzata, Bogaczewicz, Jarosław, Woźniacka, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Termedia Publishing House 2020
Materias:	Review Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247064/ https://www.ncbi.nlm.nih.gov/pubmed/32467678 http://dx.doi.org/10.5114/ada.2020.93379

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