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The features of polyglutamine regions depend on their evolutionary stability
BACKGROUND: Polyglutamine regions (polyQ) are one of the most studied and prevalent homorepeats in eukaryotes. They have a particular length-dependent codon usage, which relates to a characteristic CAG-slippage mechanism. Pathologically expanded tracts of polyQ are known to form aggregates and are i...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247214/ https://www.ncbi.nlm.nih.gov/pubmed/32448113 http://dx.doi.org/10.1186/s12862-020-01626-3 |