Cargando…

Metoprolol alleviates arginine vasopressin-induced cardiomyocyte hypertrophy by upregulating the AKT1–SERCA2 cascade in H9C2 cells

BACKGROUND: Arginine vasopressin (AVP) is elevated in patients with heart failure, and the increase in the AVP concentration in plasma is positively correlated with disease severity and mortality. Metoprolol (Met) is a beta blocker that is widely used in the clinic to treat pathological cardiac hype...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Jieqiong, Lei, Yonghong, Yang, Yanping, Gao, Haibo, Gai, Zhongchao, Li, Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247229/
https://www.ncbi.nlm.nih.gov/pubmed/32489586
http://dx.doi.org/10.1186/s13578-020-00434-y