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Metoprolol alleviates arginine vasopressin-induced cardiomyocyte hypertrophy by upregulating the AKT1–SERCA2 cascade in H9C2 cells
BACKGROUND: Arginine vasopressin (AVP) is elevated in patients with heart failure, and the increase in the AVP concentration in plasma is positively correlated with disease severity and mortality. Metoprolol (Met) is a beta blocker that is widely used in the clinic to treat pathological cardiac hype...
Autores principales: | Zhao, Jieqiong, Lei, Yonghong, Yang, Yanping, Gao, Haibo, Gai, Zhongchao, Li, Xue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247229/ https://www.ncbi.nlm.nih.gov/pubmed/32489586 http://dx.doi.org/10.1186/s13578-020-00434-y |
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