Nicotinamide N-methyltransferase inhibits autophagy induced by oxidative stress through suppressing the AMPK pathway in breast cancer cells

BACKGROUND: Nicotinamide N-methyltransferase (NNMT) is highly expressed in several cancers and can regulate cell epigenetic status and various cell metabolism pathways, such as ATP synthesis and cellular stress response. We reported in our previous papers that NNMT overexpression inhibits the apopto...

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Detalles Bibliográficos
Autores principales: Yu, Haitao, Zhou, Xi, Wang, Yanzhong, Huang, Xucheng, Yang, Jun, Zeng, Jin, Li, Guoli, Xie, Xinyou, Zhang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247246/
https://www.ncbi.nlm.nih.gov/pubmed/32489327
http://dx.doi.org/10.1186/s12935-020-01279-8

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