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MRP1-Collateral Sensitizers as a Novel Therapeutic Approach in Resistant Cancer Therapy: An In Vitro and In Vivo Study in Lung Resistant Tumor

Multidrug resistance (MDR) is the main obstacle to current chemotherapy and it is mainly due to the overexpression of some efflux transporters such as MRP1. One of the most studied strategies to overcome MDR has been the inhibition of MDR pumps through small molecules, but its translation into the c...

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Detalles Bibliográficos
Autores principales: Riganti, Chiara, Giampietro, Roberta, Kopecka, Joanna, Costamagna, Costanzo, Abatematteo, Francesca Serena, Contino, Marialessandra, Abate, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247425/
https://www.ncbi.nlm.nih.gov/pubmed/32397184
http://dx.doi.org/10.3390/ijms21093333