Cargando…
MRP1-Collateral Sensitizers as a Novel Therapeutic Approach in Resistant Cancer Therapy: An In Vitro and In Vivo Study in Lung Resistant Tumor
Multidrug resistance (MDR) is the main obstacle to current chemotherapy and it is mainly due to the overexpression of some efflux transporters such as MRP1. One of the most studied strategies to overcome MDR has been the inhibition of MDR pumps through small molecules, but its translation into the c...
Autores principales: | Riganti, Chiara, Giampietro, Roberta, Kopecka, Joanna, Costamagna, Costanzo, Abatematteo, Francesca Serena, Contino, Marialessandra, Abate, Carmen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247425/ https://www.ncbi.nlm.nih.gov/pubmed/32397184 http://dx.doi.org/10.3390/ijms21093333 |
Ejemplares similares
-
Multifunctional thiosemicarbazones targeting sigma receptors: in vitro and in vivo antitumor activities in pancreatic cancer models
por: Niso, Mauro, et al.
Publicado: (2021) -
Multi-Target Directed Ligands (MTDLs) Binding the σ(1) Receptor as Promising Therapeutics: State of the Art and Perspectives
por: Abatematteo, Francesca Serena, et al.
Publicado: (2021) -
New Strategies to Overcome Resistance to Chemotherapy and Immune System in Cancer
por: Riganti, Chiara, et al.
Publicado: (2019) -
PB28, the Sigma-1 and Sigma-2 Receptors Modulator With Potent Anti–SARS-CoV-2 Activity: A Review About Its Pharmacological Properties and Structure Affinity Relationships
por: Abate, Carmen, et al.
Publicado: (2020) -
Insights into P-Glycoprotein Inhibitors: New Inducers of Immunogenic Cell Death
por: Kopecka, Joanna, et al.
Publicado: (2020)