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Glycosylation Tunes Neuroserpin Physiological and Pathological Properties

Neuroserpin (NS) is a member of the serine protease inhibitors superfamily. Specific point mutations are responsible for its accumulation in the endoplasmic reticulum of neurons that leads to a pathological condition named familial encephalopathy with neuroserpin inclusion bodies (FENIB). Wild-type...

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Detalles Bibliográficos
Autores principales: Visentin, Cristina, Broggini, Luca, Sala, Benedetta Maria, Russo, Rosaria, Barbiroli, Alberto, Santambrogio, Carlo, Nonnis, Simona, Dubnovitsky, Anatoly, Bolognesi, Martino, Miranda, Elena, Achour, Adnane, Ricagno, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247563/
https://www.ncbi.nlm.nih.gov/pubmed/32375228
http://dx.doi.org/10.3390/ijms21093235