Mitochondrial Dysfunction and Calcium Dysregulation in Leigh Syndrome Induced Pluripotent Stem Cell Derived Neurons

Leigh syndrome (LS) is the most frequent infantile mitochondrial disorder (MD) and is characterized by neurodegeneration and astrogliosis in the basal ganglia or the brain stem. At present, there is no cure or treatment for this disease, partly due to scarcity of LS models. Current models generally...

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Detalles Bibliográficos
Autores principales: Galera-Monge, Teresa, Zurita-Díaz, Francisco, Canals, Isaac, Grønning Hansen, Marita, Rufián-Vázquez, Laura, Ehinger, Johannes K., Elmér, Eskil, Martin, Miguel A., Garesse, Rafael, Ahlenius, Henrik, Gallardo, M. Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247580/
https://www.ncbi.nlm.nih.gov/pubmed/32366037
http://dx.doi.org/10.3390/ijms21093191

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