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Selective Activation of ZAK β Expression by 3-Hydroxy-2-Phenylchromone Inhibits Human Osteosarcoma Cells and Triggers Apoptosis via JNK Activation

Although various advancements in radical surgery and neoadjuvant chemotherapy have been developed in treating osteosarcoma (OS), their clinical prognosis remains poor. A synthetic chemical compound, 3-hydroxylflavone, that is reported to regulate ROS production is known to inhibit human bone osteosa...

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Detalles Bibliográficos
Autores principales:	Fu, Chien-Yao, Lay, Ing-Shiow, Shibu, Marthandam Asokan, Tseng, Yan-Shen, Kuo, Wei-Wen, Yang, Jaw-Ji, Wang, Tso-Fu, Mahalakshmi, B., Yeh, Yu-Lan, Huang, Chih-Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247666/ https://www.ncbi.nlm.nih.gov/pubmed/32397561 http://dx.doi.org/10.3390/ijms21093366

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