The Effect of Size, Maturation, Global Asphyxia, Cerebral Ischemia, and Therapeutic Hypothermia on the Pharmacokinetics of High-Dose Recombinant Erythropoietin in Fetal Sheep

High-dose human recombinant erythropoietin (rEPO) is a promising potential neuroprotective treatment in preterm and full-term neonates with hypoxic-ischemic encephalopathy (HIE). There are limited data on the pharmacokinetics of high-dose rEPO in neonates. We examined the effects of body weight, ges...

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Detalles Bibliográficos
Autores principales: Dhillon, Simerdeep K., Wassink, Guido, Lear, Christopher A., Davidson, Joanne O., Holford, Nicholas H.G., Gunn, Alistair J., Bennet, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247678/
https://www.ncbi.nlm.nih.gov/pubmed/32344930
http://dx.doi.org/10.3390/ijms21093042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247678/
https://www.ncbi.nlm.nih.gov/pubmed/32344930
http://dx.doi.org/10.3390/ijms21093042

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