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Micheliolide Enhances Radiosensitivities of p53-Deficient Non-Small-Cell Lung Cancer via Promoting HIF-1α Degradation

Micheliolide (MCL) has shown promising anti-inflammatory and anti-tumor efficacy. However, whether and how MCL enhances the sensitivity of non-small-cell lung cancer (NSCLC) to radiotherapy are still unknown. In the present paper, we found that MCL exerted a tumor cell killing effect on NSCLC cells...

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Detalles Bibliográficos
Autores principales: Kong, Peizhong, Yu, K.N., Yang, Miaomiao, Almahi, Waleed Abdelbagi, Nie, Lili, Chen, Guodong, Han, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247679/
https://www.ncbi.nlm.nih.gov/pubmed/32403326
http://dx.doi.org/10.3390/ijms21093392