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Molecular Drug Discovery of Single Ginsenoside Compounds as a Potent Bruton’s Tyrosine Kinase Inhibitor

Bruton’s tyrosine kinase (BTK) is known as a direct regulator of inflammasome, which is an intracellular target to therapeutically modulate innate immunity. Although there is great interest in developing small molecule-based drugs with BTK inhibition, there are only a few drugs available in the mark...

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Detalles Bibliográficos
Autores principales: Lee, Keun Woo, Lee, Woong Hee, Han, Baek-Soo, Lee, Jin Ha, Doo, Eun Kyung, Kim, Jeong-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247683/
https://www.ncbi.nlm.nih.gov/pubmed/32357562
http://dx.doi.org/10.3390/ijms21093065