Cargando…

Targeting Mitochondrial Network Architecture in Down Syndrome and Aging

Mitochondria are organelles that mainly control energy conversion in the cell. In addition, they also participate in many relevant activities, such as the regulation of apoptosis and calcium levels, and other metabolic tasks, all closely linked to cell viability. Functionality of mitochondria appear...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mollo, Nunzia, Cicatiello, Rita, Aurilia, Miriam, Scognamiglio, Roberta, Genesio, Rita, Charalambous, Maria, Paladino, Simona, Conti, Anna, Nitsch, Lucio, Izzo, Antonella
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247689/ https://www.ncbi.nlm.nih.gov/pubmed/32365535 http://dx.doi.org/10.3390/ijms21093134

Ejemplares similares

Human Trisomic iPSCs from Down Syndrome Fibroblasts Manifest Mitochondrial Alterations Early during Neuronal Differentiation
por: Mollo, Nunzia, et al.
Publicado: (2021)

Mitochondrial dysfunction in down syndrome: molecular mechanisms and therapeutic targets
por: Izzo, Antonella, et al.
Publicado: (2018)

Overexpression of the Hsa21 Transcription Factor RUNX1 Modulates the Extracellular Matrix in Trisomy 21 Cells
por: Mollo, Nunzia, et al.
Publicado: (2022)

Genetics and Molecular Basis of Congenital Heart Defects in Down Syndrome: Role of Extracellular Matrix Regulation
por: Mollo, Nunzia, et al.
Publicado: (2023)

Overexpression of Chromosome 21 miRNAs May Affect Mitochondrial Function in the Hearts of Down Syndrome Fetuses
por: Izzo, Antonella, et al.
Publicado: (2017)

Pioglitazone Improves Mitochondrial Organization and Bioenergetics in Down Syndrome Cells
por: Mollo, Nunzia, et al.
Publicado: (2019)

Corrigendum: Pioglitazone Improves Mitochondrial Organization and Bioenergetics in Down Syndrome Cells
por: Mollo, Nunzia, et al.
Publicado: (2020)

Chromosomal Microarray Analysis versus Karyotyping in Fetuses with Increased Nuchal Translucency
por: Cicatiello, Rita, et al.
Publicado: (2019)

Prenatally diagnosed distal 16p11.2 microdeletion with a novel association with congenital diaphragmatic hernia: a case report
por: Genesio, Rita, et al.
Publicado: (2018)

Down Syndrome Fetal Fibroblasts Display Alterations of Endosomal Trafficking Possibly due to SYNJ1 Overexpression
por: De Rosa, Laura, et al.
Publicado: (2022)

Altered expression of mitochondrial and extracellular matrix genes in the heart of human fetuses with chromosome 21 trisomy
por: Conti, Anna, et al.
Publicado: (2007)

Short stature and primary ovarian insufficiency possibly due to chromosomal position effect in a balanced X;1 translocation
por: Genesio, Rita, et al.
Publicado: (2015)

Pure 16q21q22.1 deletion in a complex rearrangement possibly caused by a chromothripsis event
por: Genesio, Rita, et al.
Publicado: (2013)

Constitutional chromothripsis involving the critical region of 9q21.13 microdeletion syndrome
por: Genesio, Rita, et al.
Publicado: (2015)

Lithium chloride induces mesenchymal-to-epithelial reverting transition in primary colon cancer cell cultures
por: COSTABILE, VALERIA, et al.
Publicado: (2015)

Protein oligomerization modulates raft partitioning and apical sorting of GPI-anchored proteins
por: Paladino, Simona, et al.
Publicado: (2004)

New insights in the interpretation of array-CGH: autism spectrum disorder and positive family history for intellectual disability predict the detection of pathogenic variants
por: Cappuccio, Gerarda, et al.
Publicado: (2016)

Caveolin Transfection Results in Caveolae Formation but Not Apical Sorting of Glycosylphosphatidylinositol (GPI)-anchored Proteins in Epithelial Cells
por: Lipardi, Concetta, et al.
Publicado: (1998)

Apparent recessive inheritance of sideroblastic anemia type 2 due to uniparental isodisomy at the SLC25A38 locus
por: Andolfo, Immacolata, et al.
Publicado: (2020)

Regulation of sub-compartmental targeting and folding properties of the Prion-like protein Shadoo
por: Pepe, Anna, et al.
Publicado: (2017)

Mitochondrial fragmentation and network architecture in degenerative diseases
por: Shah, Syed I., et al.
Publicado: (2019)

Inhibition of 37/67kDa Laminin-1 Receptor Restores APP Maturation and Reduces Amyloid-β in Human Skin Fibroblasts from Familial Alzheimer’s Disease
por: Bhattacharya, Antaripa, et al.
Publicado: (2020)

M170. GENETIC CHARACTERIZATION OF A COHORT OF PATIENTS AFFECTED BY SCHIZOPHRENIA. THE ROLE FOR RARE STRUCTURAL VARIANTS IN MODULATING TREATMENT RESISTANT ENDOPHENOTYPES: PRELIMINARY DATA
por: Barone, Annarita, et al.
Publicado: (2020)

Complete Sequence, Multichromosomal Architecture and Transcriptome Analysis of the Solanum tuberosum Mitochondrial Genome
por: Varré, Jean-Stéphane, et al.
Publicado: (2019)

Top-Down Machine Learning-Based Architecture for Cyberattacks Identification and Classification in IoT Communication Networks
por: Abu Al-Haija, Qasem
Publicado: (2022)

Prevalence of Malocclusions in Down Syndrome Population: A Cross-Sectional Study
por: Alessandri-Bonetti, Anna, et al.
Publicado: (2023)

The thyroid hormone activating enzyme, type 2 deiodinase, induces myogenic differentiation by regulating mitochondrial metabolism and reducing oxidative stress
por: Sagliocchi, Serena, et al.
Publicado: (2019)

Architecture of the Mitochondrial Calcium Uniporter
por: Oxenoid, Kirill, et al.
Publicado: (2016)

Mechanisms of Modulation of Mitochondrial Architecture
por: Muñoz, Juan Pablo, et al.
Publicado: (2023)

A novel CISD2 intragenic deletion, optic neuropathy and platelet aggregation defect in Wolfram syndrome type 2
por: Mozzillo, Enza, et al.
Publicado: (2014)

Tracking down the molecular architecture of the synaptonemal complex by expansion microscopy
por: Zwettler, Fabian U., et al.
Publicado: (2020)

An individual differences analysis of the neurocognitive architecture of the semantic system at rest
por: Mollo, Giovanna, et al.
Publicado: (2016)

Path Integration and Cognitive Mapping Capacities in Down and Williams Syndromes
por: Bostelmann, Mathilde, et al.
Publicado: (2020)

Cervicofacial Infections Caused by Staphylococcus aureus
por: Lazarte, Carlos, et al.
Publicado: (2019)

Duodenal gangliocytic paraganglioma, a rare entity among GEP-NET: a case report with immunohistochemical and molecular study
por: Tatangelo, Fabiana, et al.
Publicado: (2014)

The 37/67kDa laminin receptor (LR) inhibitor, NSC47924, affects 37/67kDa LR cell surface localization and interaction with the cellular prion protein
por: Sarnataro, Daniela, et al.
Publicado: (2016)

Expectations About Future Economic Prospects and Satisfaction with Democracy: Evidence from European Countries during the COVID-19 Crisis
por: De Simone, Elina, et al.
Publicado: (2021)

βIII-Tubulin Structural Domains Regulate Mitochondrial Network Architecture in an Isotype-Specific Manner
por: Parker, Amelia L., et al.
Publicado: (2022)

Fatal varicella pneumonia in an unvaccinated child with Down Syndrome: a case report
por: Valentini, Diletta, et al.
Publicado: (2016)

Computerized physical and cognitive training improves the functional architecture of the brain in adults with Down syndrome: A network science EEG study
por: Anagnostopoulou, Alexandra, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_j536lgrgk0n40plo3lg8d7muso