Cargando…

Magnetic Targeting of HU-MSCs in the Treatment of Glucocorticoid-Associated Osteonecrosis of the Femoral Head Through Akt/Bcl2/Bad/Caspase-3 Pathway

PURPOSE: Osteonecrosis of the femoral head (ONFH) is a chronic and irreversible disease that eventually develops into a joint collapse and results in joint dysfunction. Early intervention and treatment are essential for preserving the joints and avoiding hip replacement. In this study, a system of h...

Descripción completa

Detalles Bibliográficos
Autores principales:	Duan, Lian, Zuo, Jianlin, Zhang, Fuqiang, Li, Binxi, Xu, Zhonghang, Zhang, Hao, Yang, Bai, Song, Wenzhi, Jiang, Jinlan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247730/ https://www.ncbi.nlm.nih.gov/pubmed/32547017 http://dx.doi.org/10.2147/IJN.S244453

Ejemplares similares

Magnetic Targeting of HU-MSCs in the Treatment of Glucocorticoid-Associated Osteonecrosis of the Femoral Head Through Akt/Bcl2/Bad/Caspase-3 Pathway [Corrigendum]
Publicado: (2021)

Exosomes derived from human platelet-rich plasma prevent apoptosis induced by glucocorticoid-associated endoplasmic reticulum stress in rat osteonecrosis of the femoral head via the Akt/Bad/Bcl-2 signal pathway
por: Tao, Shi-Cong, et al.
Publicado: (2017)

Role of coagulopathy in glucocorticoid-induced osteonecrosis of the femoral head
por: Zhang, Qiankun, et al.
Publicado: (2017)

Administration of mircoRNA‐135b‐reinforced exosomes derived from MSCs ameliorates glucocorticoid‐induced osteonecrosis of femoral head (ONFH) in rats
por: Zhang, Xiang, et al.
Publicado: (2020)

Administration of erythropoietin exerts protective effects against glucocorticoid-induced osteonecrosis of the femoral head in rats
por: CHEN, SEN, et al.
Publicado: (2014)

Icariin promotes angiogenesis in glucocorticoid‐induced osteonecrosis of femoral heads: In vitro and in vivo studies
por: Yu, Huachen, et al.
Publicado: (2019)

SIRT6 Prevents Glucocorticoid-Induced Osteonecrosis of the Femoral Head in Rats
por: Fang, Lun, et al.
Publicado: (2022)

The Protective Effect of Luteolin in Glucocorticoid-Induced Osteonecrosis of the Femoral Head
por: Yan, Zijian, et al.
Publicado: (2020)

Valproic acid prevents glucocorticoid-induced osteonecrosis of the femoral head of rats
por: Zhou, Ding, et al.
Publicado: (2018)

Vitamin K(2) Prevents Glucocorticoid-induced Osteonecrosis of the Femoral Head in Rats
por: Zhang, Yue-Lei, et al.
Publicado: (2016)

Less sclerotic microarchitecture pattern with increased bone resorption in glucocorticoid-associated osteonecrosis of femoral head as compared to alcohol-associated osteonecrosis of femoral head
por: Chen, Yiwei, et al.
Publicado: (2023)

The Pathophysiological Sequence of Glucocorticoid-Induced Osteonecrosis of the Femoral Head in Male Mice
por: Weinstein, Robert S., et al.
Publicado: (2017)

Glucocorticoids in osteonecrosis of the femoral head: A new understanding of the mechanisms of action
por: Kerachian, Mohammad Amin, et al.
Publicado: (2009)

Glucocorticoids induce osteonecrosis of the femoral head through the Hippo signaling pathway
por: Li, Yugang, et al.
Publicado: (2021)

Altered lipidomic profiles in patients with and without osteonecrosis of the femoral head after 1‐month glucocorticoid treatment
por: Wang, Xin‐Yuan, et al.
Publicado: (2021)

Screening and identification of potential key biomarkers for glucocorticoid-induced osteonecrosis of the femoral head
por: Chen, Dan, et al.
Publicado: (2023)

Decreased angiogenic and increased apoptotic activities of bone microvascular endothelial cells in patients with glucocorticoid-induced osteonecrosis of the femoral head
por: Yu, Huachen, et al.
Publicado: (2020)

Vitamin B(2) Prevents Glucocorticoid-Caused Damage of Blood Vessels in Osteonecrosis of the Femoral Head
por: Guo, MinKang, et al.
Publicado: (2022)

Polarization Behavior of Bone Macrophage as Well as Associated Osteoimmunity in Glucocorticoid-Induced Osteonecrosis of the Femoral Head
por: Zhang, Qingyu, et al.
Publicado: (2023)

Inhibition of PERK Signaling Prevents Against Glucocorticoid-induced Endotheliocyte Apoptosis and Osteonecrosis of the Femoral Head
por: Gao, Yanchun, et al.
Publicado: (2020)

High-energy focused extracorporeal shock wave prevents the occurrence of glucocorticoid-induced osteonecrosis of the femoral head: A prospective randomized controlled trial()
por: Yang, Xu, et al.
Publicado: (2022)

Identification and Validation of Potential Ferroptosis-Related Genes in Glucocorticoid-Induced Osteonecrosis of the Femoral Head
por: Chen, Ning, et al.
Publicado: (2023)

Glucocorticoids induce osteonecrosis of the femoral head in rats via PI3K/AKT/FOXO1 signaling pathway
por: Sun, Fei, et al.
Publicado: (2022)

Inhibition of PERK Signaling Prevents Against Glucocorticoid-induced Endotheliocyte Apoptosis and Osteonecrosis of the Femoral Head: Erratum
por: Gao, Yanchun, et al.
Publicado: (2021)

Glucocorticoids: bad or safe for the bones?
por: Lems, Willem F
Publicado: (2015)

Metabolic Profiling Analysis of the Effect and Mechanism of Gushiling Capsule in Rabbits With Glucocorticoid-Induced Osteonecrosis of the Femoral Head
por: Mei, Runhong, et al.
Publicado: (2022)

Lithium chloride prevents glucocorticoid-induced osteonecrosis of femoral heads and strengthens mesenchymal stem cell activity in rats
por: Zhang, Yue-Lei, et al.
Publicado: (2021)

Investigating Clinical Failure of Bone Grafting through a Window at the Femoral Head Neck Junction Surgery for the Treatment of Osteonecrosis of the Femoral Head
por: Zuo, Wei, et al.
Publicado: (2016)

Effects of Simvastatin on Cartilage Homeostasis in Steroid-Induced Osteonecrosis of Femoral Head by Inhibiting Glucocorticoid Receptor
por: Yu, Yaling, et al.
Publicado: (2022)

HGF-Transgenic MSCs Can Improve the Effects of Tissue Self-Repair in a Rabbit Model of Traumatic Osteonecrosis of the Femoral Head
por: Wen, Qian, et al.
Publicado: (2012)

Osteoimmunology and osteonecrosis of the femoral head
por: Ma, Maoxiao, et al.
Publicado: (2022)

Inhibition of MAGL activates the Keap1/Nrf2 pathway to attenuate glucocorticoid‐induced osteonecrosis of the femoral head
por: Yang, Ning, et al.
Publicado: (2021)

Osteonecrosis of the Femoral Head
por: George, Gary, et al.
Publicado: (2022)

Bcl-xL overexpression decreases GILZ levels and inhibits glucocorticoid-induced activation of caspase-8 and caspase-3 in mouse thymocytes
por: Muscari, Isabella, et al.
Publicado: (2020)

Correction: Investigating Clinical Failure of Bone Grafting through a Window at the Femoral Head Neck Junction Surgery for the Treatment of Osteonecrosis of the Femoral Head
por: Zuo, Wei, et al.
Publicado: (2016)

Activation of cannabinoid receptor 2 alleviates glucocorticoid-induced osteonecrosis of femoral head with osteogenesis and maintenance of blood supply
por: Sun, Houyi, et al.
Publicado: (2021)

Combined Pharmacotherapy with Alendronate and Desferoxamine Regulate the Bone Resorption and Bone Regeneration for Preventing Glucocorticoids-Induced Osteonecrosis of the Femoral Head
por: Sheng, Hongfeng, et al.
Publicado: (2020)

Exosomes from Human Synovial-Derived Mesenchymal Stem Cells Prevent Glucocorticoid-Induced Osteonecrosis of the Femoral Head in the Rat
por: Guo, Shang-Chun, et al.
Publicado: (2016)

Phase-contrast imaging with synchrotron hard X-ray reveals the effect of icariin on bone tissue morphology and microstructure in rabbits with early glucocorticoid-induced osteonecrosis of the femoral head
por: Yang, Xu, et al.
Publicado: (2023)

The use of anticoagulants for prevention and treatment of osteonecrosis of the femoral head: A systematic review
por: Guo, Peipei, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_j55a9vrg8b1nehc8jpugqakb9t