Repurposing Quaternary Ammonium Compounds as Potential Treatments for COVID-19

The COVID-19 pandemic has highlighted an important role for drug repurposing. Quaternary ammonium compounds such as ammonium chloride, cetylpyridinium and miramistin represent widely accessible antiseptic molecules with well-known broad-spectrum antiviral activities and represent a repurposing oppor...

Descripción completa

Detalles Bibliográficos
Autores principales: Baker, Nancy, Williams, Antony J., Tropsha, Alexander, Ekins, Sean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247743/
https://www.ncbi.nlm.nih.gov/pubmed/32451736
http://dx.doi.org/10.1007/s11095-020-02842-8
Descripción
Sumario:The COVID-19 pandemic has highlighted an important role for drug repurposing. Quaternary ammonium compounds such as ammonium chloride, cetylpyridinium and miramistin represent widely accessible antiseptic molecules with well-known broad-spectrum antiviral activities and represent a repurposing opportunity as therapeutics against SARS-CoV-2. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s11095-020-02842-8) contains supplementary material, which is available to authorized users.

Ejemplares similares