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Demonstration of Binding Induced Structural Plasticity in a SH2 Domain

SH2 domains are common protein interaction domains able to recognize short aminoacidic sequences presenting a phosphorylated tyrosine (pY). In spite of their fundamental importance for cell physiology there is a lack of information about the mechanism by which these domains recognize and bind their...

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Detalles Bibliográficos
Autores principales:	Visconti, Lorenzo, Toto, Angelo, Jarvis, James A., Troilo, Francesca, Malagrinò, Francesca, De Simone, Alfonso, Gianni, Stefano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247818/ https://www.ncbi.nlm.nih.gov/pubmed/32528972 http://dx.doi.org/10.3389/fmolb.2020.00089

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