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Nucleoporin 153 links nuclear pore complex to chromatin architecture by mediating CTCF and cohesin binding
Nucleoporin proteins (Nups) have been proposed to mediate spatial and temporal chromatin organization during gene regulation. Nevertheless, the molecular mechanisms in mammalian cells are not well understood. Here, we report that Nucleoporin 153 (NUP153) interacts with the chromatin architectural pr...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248104/ https://www.ncbi.nlm.nih.gov/pubmed/32451376 http://dx.doi.org/10.1038/s41467-020-16394-3 |