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Nucleoporin 153 links nuclear pore complex to chromatin architecture by mediating CTCF and cohesin binding

Nucleoporin proteins (Nups) have been proposed to mediate spatial and temporal chromatin organization during gene regulation. Nevertheless, the molecular mechanisms in mammalian cells are not well understood. Here, we report that Nucleoporin 153 (NUP153) interacts with the chromatin architectural pr...

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Detalles Bibliográficos
Autores principales: Kadota, Shinichi, Ou, Jianhong, Shi, Yuming, Lee, Jeannie T., Sun, Jiayu, Yildirim, Eda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248104/
https://www.ncbi.nlm.nih.gov/pubmed/32451376
http://dx.doi.org/10.1038/s41467-020-16394-3

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